Results 171 to 180 of about 47,711 (290)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Brain sparing and the blood brain barrier-bridging the preclinical to clinical gap. [PDF]

Pediatr Res
White TA, Miller SL.
europepmc   +1 more source

Syndrome de Raynaud d’origine médicamenteuse suivant l’amorce d’un traitement par le succinate de métoprolol. [PDF]

CMAJ
Sahoo S, Gavin MC, Cluett JL.
europepmc   +1 more source

The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Activation of both the metaboreflex via post‐exercise circulatory occlusion and the chemoreflex via acute and chronic hypoxia increased pulmonary artery systolic pressure. Coactivation of these reflexes further increased pulmonary artery pressure in an additive manner.
Lauren E. Maier, Elliott J. Jenkins, Andrew Douglas, Jack Talbot, Alexandra Williams, Jonathan Moore, Craig D. Steinback, Liam D. Corr, Zoe H. Adams, Fabio Giuseppe Laginestra, Markus Amann, Philip N. Ainslie, Travis D. Gibbons, Mike Stembridge   +13 more
wiley   +1 more source

Correction: The mineralocorticoid receptor antagonist finerenone enhances cardiovascular recovery upon food intake normalization in obese mice. [PDF]

Cardiovasc Diabetol
Monmirel-Fauconnier M, Pieronne-Deperrois M, Bonnard B, Frimat C, Linghui K, Dheasmhunaigh AN, Nicol L, Morchid S, Renet S, Dumesnil A, Richard V, Fève B, Jaisser F, Boulkroun S, Mulder P, Ouvrard-Pascaud A.   +15 more
europepmc   +1 more source

When the lungs speak to the brain: a new reflex pathway in the neural control of circulation during exercise?

The Journal of Physiology, EarlyView.
Lauro C. Vianna
wiley   +1 more source

Functional expression of inwardly rectifying and ATP-sensitive potassium channels in human pulmonary artery smooth muscle and endothelial cells. [PDF]

J Physiol
Barreira B, Morales-Cano D, Moreno L, de Olaiz B, Adão R, Cogolludo A, Perez-Vizcaino F, Sancho M.   +7 more
europepmc   +1 more source

On the adaptive significance of group III/IV muscle afferent feedback for the cardiovascular response during sustained locomotion in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Group III/IV leg muscle afferent feedback has previously been recognized as an important determinant of the cardiovascular response to exercise lasting <5 min. Here we demonstrate that the activity of these neurons is crucial in regulating central and peripheral haemodynamic responses during steady state exercise of longer ...
D. Iannetta, F. G. Laginestra, T. S. Thurston, R. H. Jenkinson, J. Chang, H.‐Y. Wan, R. M. Broxterman, J. C. Weavil, M. Amann   +8 more
wiley   +1 more source

Modulation of cell fate by shock wave therapy: commentary. [PDF]

Eur Heart J Open
Jargin SV.
europepmc   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe, Michael Apollinaro, Joanna Reeves, Christopher Nester, Leah R. Bent   +4 more
wiley   +1 more source