Results 231 to 240 of about 140,646 (292)

Impacts of exercise, renin–angiotensin system modulation or both on skeletal muscle circadian gene expression

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro   +8 more
wiley   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

open access: yesExperimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti   +6 more
wiley   +1 more source

Individuals with persisting post‐concussion symptoms with physiological subtype demonstrate altered cardiovascular and autonomic responses to face cooling

open access: yesExperimental Physiology, EarlyView.
Abstract Individuals with persisting post‐concussion symptoms with physiological subtype (PPCS‐P) demonstrate exercise intolerance due to exacerbation of concussion‐like symptoms during incremental exercise. We tested the hypothesis that individuals with PPCS‐P (n = 12) would have a blunted cardiac autonomic response to face cooling compared to healthy
Phillip J. Wallace   +6 more
wiley   +1 more source

Central cytometabolic functional vascular coupling in health and disease. [PDF]

open access: yesNPJ Metab Health Dis
Sims SL   +7 more
europepmc   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

open access: yesExperimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto   +2 more
wiley   +1 more source

Portopulmonary Hypertension and Hepatopulmonary Syndrome: Contrasting Pathophysiology and Implications for Liver Transplantation. [PDF]

open access: yesJ Clin Med
Silić V   +8 more
europepmc   +1 more source

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

open access: yesExperimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

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