Results 211 to 220 of about 174,305 (306)

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

Pre‐anaesthetic risk assessment and management of dogs with myxomatous mitral valve disease: a spectrum of care narrative review

open access: yesJournal of Small Animal Practice, EarlyView.
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon   +3 more
wiley   +1 more source

The nitrate-nitrite-nitric oxide pathway of neuroinflammation and cognitive impairment in ischemic stroke. [PDF]

open access: yesFront Immunol
Liu J   +9 more
europepmc   +1 more source

Sleep Disordered Breathing Severity Alters Overnight Temperature Changes in Children

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT The quality of sleep is very closely related to variations in body temperature. We aimed to assess the feasibility of skin temperature measurements in children attending the sleep laboratory for routine polysomnography and to determine whether there was a difference in body temperature between children with different severities of sleep ...
Georgina Plunkett   +8 more
wiley   +1 more source

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata   +3 more
wiley   +1 more source

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