Results 31 to 40 of about 204,625 (386)
Diabetologia, 2017 Aims/hypothesisSodium–glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) constitute a novel class of glucose-lowering (type 2) kidney-targeted agents. We recently reported that the SGLT2i empagliflozin (EMPA) reduced cardiac cytosolic Na+ ([Na+]c) and ...
L. Uthman +10 more
semanticscholar +1 more source
Molecules, 2022 Vanillin is a phenolic aldehyde, which is found in plant species of the Vanilla genus. Although recent studies have suggested that vanillin has various beneficial properties, the effect of vanillin on blood vessels has not been studied well.
Sooyeon Choi +5 more
doaj +1 more source
Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. [PDF]
, 2019 There is a limit beyond which increasing either the concentration of a prostaglandin analog (PGA) or its dosing frequency fails to produce increases in ocular hypotensive efficacy with topical dosing.
Alm +36 more
core +2 more sources
Journal of the American Medical Association (JAMA), 2019 Importance Short-term infusions of single vasodilators, usually given in a fixed dose, have not improved outcomes in patients with acute heart failure (AHF).
N. Kozhuharov +28 more
semanticscholar +1 more source
Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease
Pulmonary Circulation, 2022 Pulmonary veno‐occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH) is a rare subtype of pulmonary hypertension with dismal prognosis.
Junichi Nakamura +12 more
doaj +1 more source
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. [PDF]
, 2016 Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics. Brimonidine is a selective α2-adrenergic receptor (AR) agonist approved for persistent facial erythema of rosacea based on significant efficacy and
Detmar, Michael +6 more
core +2 more sources
A Critical Role for Astrocytes in Hypercapnic Vasodilation in Brain
Journal of Neuroscience, 2017 Cerebral blood flow (CBF) is controlled by arterial blood pressure, arterial CO2, arterial O2, and brain activity and is largely constant in the awake state.
C. Howarth +13 more
semanticscholar +1 more source
Current concepts of active vasodilation in human skin
Temperature, 2016 In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in ...
B. Wong, Casey G. Hollowed
semanticscholar +1 more source
Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels.
American Journal of Physiology. Heart and Circulatory Physiology, 2016 Hydrogen sulfide (H2S) is a recently described gaseous vasodilator produced within the vasculature by the enzymes cystathionine γ-lyase and 3-mercaptopyruvate sulfurtransferase.
J. Naik, J. Osmond, B. Walker, N. Kanagy
semanticscholar +1 more source
Searching the ideal inhaled vasodilator: From nitric oxide to prostacyclin [PDF]
, 2002 Today, the technique to directly administer vasodilators via the airway to treat pulmonary hypertension and to improve pulmonary gas exchange is widely accepted among clinicians.
Habler, Oliver +5 more
core +1 more source