Results 141 to 150 of about 53,380 (285)

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Structure–activity relationship of the allosteric effects of ivermectin at human P2X4 and GABAA receptors

British Journal of Pharmacology, Volume 182, Issue 21, Page 5286-5302, November 2025.
Abstract Background and purpose Positive allosteric modulation of the P2X4 receptor is a potential route to providing cardiovascular benefit through enhancing flow‐dependent arterial vasodilation and providing cardioprotection. However, ligands that selectively enhance P2X4 activity are absent.
Jessica L. Meades, Marcella Bassetto, Marius C. Staiculescu, Gayathri Swaminath, Samuel J. Fountain   +4 more
wiley   +1 more source

Polyvinylpyrrolidone-coated gold nanoparticles inhibit endothelial cell viability, proliferation, and ERK1/2 phosphorylation and reduce the magnitude of endothelial-independent dilator responses in isolated aortic vessels

International Journal of Nanomedicine, 2017
Teba Mohamed,1,* Sabine Matou-Nasri,2,* Asima Farooq,3 Debra Whitehead,3 May Azzawi1 1School of Healthcare Science, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK; 2Cell and Gene Therapy Group, Medical Genomics ...
Mohamed T, Matou-Nasri S, Farooq A, Whitehead D, Azzawi M   +4 more
doaj  

-153-THE MYOCARDIAL FUNCTION UNDER THE REPERFUSED MYOCARDIUM : THE EFFECTS OF VASODILATOR AND INOTROPIC AGENT

, 1986
Takashi Saito, Mamoru Miura, Yoshikazu Tamura, Yuichi Chiba, Nobuo Yuasa, Kouichi Yoshida, Hitoshi Matsuoka, Takehiko Tajika, Shinitsu Sato, Toyohiko Abe, Tadaya Sato, Yoshihisa Abe, Yoshiaki Kaga, Yasushi Suzuki, Shigeaki Ikeda, Tomohiro Kanazawa   +15 more
openalex   +2 more sources

Agents with vasodilator properties in acute heart failure: how to design successful trials [PDF]

, 2015
Alexandre Mebazaa, Dan Longrois, Marco Metra, Christian Mueller, Mark Richards, Lothar Roessig, Marie France Séronde, Naoki Sato, Norman Stockbridge, Wendy Gattis Stough, Ángeles Alonso, Robert Cody, Nancy Cook Bruns, Mihai Gheorghiade, Johannes Holzmeister, Sai͏̈d Laribi, Faı̈ez Zannad   +16 more
openalex   +1 more source

Modification by vasodilator agents of reoxygention- and calcium- induced contractions in isolated dog cerebral arteries.

, 1989
Ka Bian, Masahisa Kawakami, Kazuhide Ayajiki, Noboru Toda   +3 more
openalex   +1 more source

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome [PDF]

, 2018
Julia Schümann, Eva C Henrich, Hellen Strobl, Roland Prondzinsky, Sophie Weiche, Hölger Thiele, Karl Werdan, Stefan Frantz, Susanne Unverzagt   +8 more
openalex   +1 more source

Survey on 9 years of anti‐doping controls in horse races in Italy

Equine Veterinary Journal, Volume 57, Issue 6, Page 1592-1599, November 2025.
Abstract Background Doping in racehorses is a threat to horse welfare and the integrity of the sport. Despite its relevance, the literature on the prevalence of anti‐doping violations worldwide is limited. Objectives To analyse anti‐doping violations in racehorses in Italy. Study Design Retrospective observational study.
Mariana Roccaro, Riccardo Rinnovati, Luca Stucchi, Federica La Rocca, Giuseppe Cascio, Angelo Peli   +5 more
wiley   +1 more source

Cardiovascular Effects of NSP-804 and NSP-805, Novel Cardiotonic Agents with Vasodilator Properties

, 1993
Nobuo Mochizuki, Seiichi Uchida, Hiroo Miyata   +2 more
openalex   +1 more source

Hemodynamic effects of vasodilator agents in dogs with experimental ventricular septal defects. [PDF]

, 1976
David Synhorst, Romy Lauer, Donald B. Doty, Matthew J. Brody   +3 more
openalex   +1 more source