Results 31 to 40 of about 26,374 (207)
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang +15 more
wiley +1 more source
Increased short-term blood pressure variability (BPV) is strongly correlated with target organ damage. However, the molecular mechanisms underlying abnormal BPV-induced organ damage and effective therapeutic targets are poorly understood.
Minlie Liang +4 more
doaj +1 more source
Background: Neurocardiac dysfunction worsens clinical outcome and increases mortality in stroke survivors. We hypothesized that heart rate variability (HRV) biofeedback improves neurocardiac function by modulating autonomic nervous system activity after ...
Timo Siepmann +10 more
doaj +1 more source
Effects of systemic ethanol on medullary vasomotor neurons and baroreflexes
The acute effects of systemic ethanol on reticulospinal sympathoexcitatory neurons were examined in vivo in anesthetized, paralyzed rats. Ethanol (0.45 g/kg, i.v.) potentiated the depressant effect of locally applied gamma-aminobutyric acid (GABA) but attenuated the excitatory effect of L-glutamate.
M K, Sun, D J, Reis
openaire +2 more sources
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen +11 more
wiley +1 more source
Slow gait speed – an indicator of lower cerebral vasoreactivity in type 2 diabetes mellitus
Objective: Gait speed is an important predictor of health that is negatively affected by aging and type 2 diabetes. Diabetes has been linked to reduced vasoreactivity, i.e. the capacity to regulate cerebral blood flow in response to CO2 challenges.
Azizah J Jor'dan +3 more
doaj +1 more source
Abnormal Vasomotor System Function in Idiopathic Generalized Epileptic Patients
OBJECTIVE: Autonomic dysfunction is widely recognized in both partial and generalized epilepsies. The aim of this study was to evaluate the vasomotor response in patients with generalized idiopathic epilepsy by the clinical autonomic function tests. METHODS: 124 consecutive subjects including 62 idiopathic generalized epileptic patients diagnosed for ...
Mehdi Maghbooli +3 more
openaire +2 more sources
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Types of Pain in Multiple System Atrophy
Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese +19 more
wiley +1 more source
ABSTRACT Purpose To directly quantify respiration‐driven cerebrovascular resistance dynamics (CRD) using a gas‐free MRI framework based on the internal‐to‐external artery carotid flow ratio (ratio_Q). Theory and Methods Two independent datasets (n = 10 and n = 17) were used to evaluate repeatability and to compare breathing conditions.
Pan Liu +5 more
wiley +1 more source

