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The Biology of Vasopressin [PDF]

Biomedicines, 2021
Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for adapting to terrestrial environments.
Samantha Sparapani, Cassandra Millet-Boureima, Joshua Oliver, Kathy Mu, Pegah Hadavi, Tamar Kalostian, Nazifa Ali, Carla Maria Avelar, Marion Bardies, Brenton Barrow, Minky Benedikt, Giuliana Biancardi, Raminder Bindra, Lisa Bui, Zakaria Chihab, Ashley Cossitt, Jeffrey Costa, Tina Daigneault, Jocelyn Dault, Isa Davidson, Jonathan Dias, Emie Dufour, Sabine El-Khoury, Nargess Farhangdoost, Anika Forget, Alexa Fox, Myriam Gebrael, Maria Concetta Gentile, Olivia Geraci, Ansley Gnanapragasam, Elias Gomah, Elie Haber, Claudia Hamel, Thivya Iyanker, Christina Kalantzis, Sara Kamali, Elsa Kassardjian, Hryssi Krissy Kontos, Thi Bich Uyen Le, Daniella LoScerbo, Yan Fang Low, Danielle Mac Rae, Flore Maurer, Sana Mazhar, Alice Nguyen, Kathy Nguyen-Duong, Chelsea Osborne-Laroche, Hwi Wun Park, Emilie Parolin, Kahlila Paul-Cole, Leah Sarah Peer, Margaux Philippon, Charles-Alexandre Plaisir, Jessica Porras Marroquin, Simran Prasad, Rewaparsad Ramsarun, Saad Razzaq, Samantha Rhainds, Damien Robin, Ryan Scartozzi, Davindra Singh, Sajad Soleimani Fard, Maxim Soroko, Nastaran Soroori Motlagh, Kiri Stern, Laila Toro, M. Wyatt Toure, Stephanie Tran-Huynh, Sarah Trépanier-Chicoine, Claudia Waddingham, Aaliyah Jasmine Weekes, Allison Wisniewski, Chiara Gamberi   +72 more
doaj   +5 more sources

Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor

JCI Insight, 2021
Subjects with obesity frequently have elevated serum vasopressin levels, noted by measuring the stable analog, copeptin. Vasopressin acts primarily to reabsorb water via urinary concentration. However, fat is also a source of metabolic water, raising the
Ana Andres-Hernando, Thomas J. Jensen, Masanari Kuwabara, David J. Orlicky, Christina Cicerchi, Nanxing Li, Carlos A. Roncal-Jimenez, Gabriela E. Garcia, Takuji Ishimoto, Paul S. Maclean, Petter Bjornstad, Laura Gabriela Sanchez-Lozada, Mehmet Kanbay, Takahiko Nakagawa, Richard J. Johnson, Miguel A. Lanaspa   +15 more
doaj   +2 more sources

Vasopressin and its analogues in shock states: a review

Annals of Intensive Care, 2020
Activation of arginine–vasopressin is one of the hormonal responses to face vasodilation-related hypotension. Released from the post-pituitary gland, vasopressin induces vasoconstriction through the activation of V1a receptors located on vascular smooth ...
Julien Demiselle, Nicolas Fage, Peter Radermacher, Pierre Asfar   +3 more
doaj   +2 more sources

Vasopressin Is Not Associated With Severe Kidney Injury in Liver Transplantation: A Propensity Score-adjusted Analysis [PDF]

Transplantation Direct
Background. Hypotension during liver transplantation often requires vasopressor therapy. Acute kidney injury is a common complication after liver transplantation.
Edoardo Antonucci, MD, Michael P. Bokoch, MD, PhD, Dieter Adelmann, MD, PhD, Kerstin Kolodzie, MD, PhD, MAS, Garrett R. Roll, MD, Elizabeth Sun, MD, Matthieu Legrand, MD, PhD, Rishi Kothari, MD   +7 more
doaj   +2 more sources

Neuromodulation by Oxytocin and Vasopressin [PDF]

Neuron, 2012
Oxytocin (OT) and vasopressin (VP) are two closely related neuropeptides, widely known for their peripheral hormonal effects. Specific receptors have also been found in the brain, where their neuromodulatory actions have meanwhile been described in a large number of regions.
R. Stoop
semanticscholar   +4 more sources

Vasopressin–aquaporin-2 pathway: recent advances in understanding water balance disorders [version 1; referees: 3 approved]

F1000Research, 2019
The alteration of water balance and related disorders has emerged as being strictly linked to the state of activation of the vasopressin–aquaporin-2 (vasopressin–AQP2) pathway.
Marianna Ranieri, Annarita Di Mise, Grazia Tamma, Giovanna Valenti   +3 more
doaj   +2 more sources

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities.

Endocrinology, 2022
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine concentration, respectively.
Nicole Rigney, G. J. de Vries, A. Petrulis, L. Young   +3 more
semanticscholar   +1 more source

α-Actinin 4 Links Vasopressin Short-Term and Long-Term Regulation of Aquaporin-2 in Kidney Collecting Duct Cells

Frontiers in Physiology, 2021
Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho, Hsiu-Hui Yang, Shih-Han Su, Ai-Hsin Yeh, Ming-Jiun Yu   +4 more
doaj   +1 more source

Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Previous trials have suggested that vasopressin and methylprednisolone administered during in-hospital cardiac arrest might improve outcomes.
L. Andersen, Dan Isbye, J. Kjærgaard, C. M. Kristensen, S. Darling, S. Zwisler, Stine Fisker, J. C. Schmidt, H. Kirkegaard, A. Grejs, Jørgen R G Rossau, J. Larsen, B. Rasmussen, S. Riddersholm, K. Iversen, M. Schultz, J. Nielsen, B. Løfgren, K. Lauridsen, Christoffer Sølling, Kim B. Pælestik, A. Kjærgaard, Dorte Due-Rasmussen, F. Folke, M. Charlot, Rikke Malene H G Jepsen, S. Wiberg, M. Donnino, T. Kurth, Maria Høybye, Birthe Sindberg, M. Holmberg, A. Granfeldt   +32 more
semanticscholar   +1 more source

Association of Arterial pH With Hemodynamic Response to Vasopressin in Patients With Septic Shock: An Observational Cohort Study

Critical Care Explorations, 2022
OBJECTIVES:. Vasopressin is reported to retain vasoconstrictive activity in the setting of acidemia, but preclinical models are inconsistent and studies have not evaluated the clinical effectiveness of vasopressin based on arterial pH.
Seth R. Bauer, PharmD, Gretchen L. Sacha, PharmD, Matthew T. Siuba, DO, Simon W. Lam, PharmD, MS, Anita J. Reddy, MD, MBA, Abhijit Duggal, MD, MPH, MSc, Vidula Vachharajani, MD   +6 more
doaj   +1 more source