Impact of Early versus Delayed Vasopressin Initiation on 28-Day Mortality in Older Adults with Septic Shock. [PDF]
Ther Clin Risk ManagLiu L, Shi H, Zhang L, Ma J.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves +4 more
wiley +1 more source
Acute hot‐water immersion augments the diastolic blood pressure nocturnal dip in healthy adults
Experimental Physiology, EarlyView.Abstract Hot‐water immersion (HWI) has been shown to reduce 24 h ambulatory systolic blood pressure in hypertensive adults and might represent a preventative strategy for maintaining cardiovascular health in normotensive adults. The purpose of this study was to determine the time course of post‐HWI hypotension and test the hypothesis that a single HWI ...
Samuel F. Leaney +8 more
wiley +1 more source
Absolute, weight-based, fixed-dose, or phenotype-guided? Rethinking the meaning of vasopressor dose in critical care. [PDF]
Ann Intensive CareSanchez-Escalante C, Wieruszewski PM.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract The cardiovascular system is strongly influenced by gravitational loading and blood volume status. Quantifying central haemodynamic and autonomic reflex responses to fluid redistribution is important in altered‐gravity conditions, with relevance to spaceflight and clinical medicine.
Adrien Robin +8 more
wiley +1 more source
Arginine vasopressin disorders, formerly known as diabetes insipidus. [PDF]
CMAJManialawy Y, Yang Y, Prebtani APH.
europepmc +1 more source
Update on cellular expression and function of ANO1 channels in urethral smooth muscle
The Journal of Physiology, EarlyView.Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
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Is thirst the missing physiological link between SGLT2 inhibitors and reduced nephrolithiasis risk? [PDF]
Clin Kidney JLombardi M, Beltrami P, Martini B.
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Mechanisms of haemoglobin mass expansion following heat stress
The Journal of Physiology, EarlyView.Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
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GABA+‐Edited Magnetic Resonance Spectroscopy Deep Learning Quality Assessment Framework
Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1028-1041, September 2026.ABSTRACT Purpose Motivated by the need to improve GABA+‐edited magnetic resonance spectroscopy (MRS) quality, we developed a three‐module framework to improve transient averaging based on quality. We hypothesized that training a deep learning (DL) model to differentiate spectrum quality could improve transient averaging compared to traditional ...
Hanna Bugler +2 more
wiley +1 more source