Results 111 to 120 of about 58,394 (261)

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

DDAVP Challenges in 170 Children With von Willebrand Disease: Response Classification Varies According to Criteria Used

Haemophilia, EarlyView.
ABSTRACT Introduction Individuals diagnosed with types 1/1C/2A/2M von Willebrand disease (VWD) typically undergo a desmopressin (DDAVP) challenge to assess therapeutic benefit. This involves measuring von Willebrand factor antigen (VWF:Ag), activity (VWF:Act; VWF:RCo/VWF:GPIbM/VWF:Ab), and coagulant factor VIII (FVIII:C) levels 0 (pre), 1, and 4‐h post‐
Michael Shu, Caroline Malcolmson, Amanda Fregonas, Tristan E. Knight, Margaret L. Rand, Cindy Wakefield, Vanessa Bouskill, Manuel Carcao   +7 more
wiley   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Modelling vasopressin synthesis and storage dynamics during prolonged osmotic challenge and recovery based on activity dependent upregulation of mRNA transcription. [PDF]

PLoS Comput Biol
MacGregor DJ.
europepmc   +1 more source

Identification and Treatment of Anorexia Nervosa in Women With Perimenopause

Journal of Midwifery &Women's Health, EarlyView.
Abstract Disordered eating is a common problem that midwives will encounter as frontline primary care providers. Anorexia nervosa (AN) is a form of disordered eating that results in chronic starvation state, creating significant risk of morbidity and mortality to the patient. AN is traditionally considered a disorder of adolescence and young adulthood;
Janell Senda, Sarah Carpenter, Mary Carter‐Orbke   +2 more
wiley   +1 more source

The CTNNB1-TRIM28 complex governs hormone-induced RNA polymerase II dynamics in kidney epithelial cells. [PDF]

Proc Natl Acad Sci U S A
Jang HJ, Park E, Jung HJ, Kwon TH.
europepmc   +1 more source

High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis

Journal of Internal Medicine, EarlyView.
Abstract Introduction Fluid restriction is the current first‐line therapy for hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD), yet up to 50% of patients do not achieve an adequate plasma sodium correction. Reported predictors of nonresponse include urine osmolality >500 mOsm/kg, the Furst ratio >1 [(UNa + UK)/(PNa)], urine ...
Michelle Patricia Müller, Laura Potasso, Ewout J. Hoorn, Julie Refardt, Mirjam Christ‐Crain, for the HIT study investigators   +5 more
wiley   +1 more source

A vasopressin gate transforms social distress into caregiving. [PDF]

J Clin Invest
Fadok JP.
europepmc   +1 more source

Vasopressin Use in Extremely Preterm Infants With Refractory Cardiopulmonary Instability: Physiological Response and Mortality‐Associated Factors

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective To evaluate the physiological response following vasopressin initiation and identify factors associated with mortality in extremely preterm infants with refractory cardiopulmonary instability. Study Design Retrospective cohort study of infants born at less than 29 weeks' gestation who received vasopressin. Physiological responses and
Faisal Alamer, Kamal Ali, Saif Alsaif, Mohanned Alrahili, Mohammed Almahdi, Eman Bazbouz, Rana Almuqati, Saad Alshareedah, Faisal Alsehli, Abdulaziz Homedi   +9 more
wiley   +1 more source

Vasopressin and microalbuminuria: is it vasopressin per se or is it salt intake? [PDF]

Kidney International, 2010
Meijer, Esther, de Jong, Paul E., Gansevoort, Ron T.   +2 more
openaire   +3 more sources