Results 101 to 110 of about 58,394 (261)

Effects of Immediate Skin‐to‐Skin Contact in Preterm Infants in High‐Resource Settings: A Systematic Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim A landmark trial published in 2021 demonstrated a 25% reduction in neonatal mortality when comparing immediate skin‐to‐skin contact (iSSC) to conventional care in infants with birthweight 1–1.8 kg in low‐ and middle‐resource settings.
Victoria Rettedal, Siren Rettedal, Maren Johanne Heilskov Rytter, Linea Grothe Larsen, Frederikke Buskov, Evalotte Mörelius, Katrin Mehler, Karoline Lode‐Kolz   +7 more
wiley   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Pediatric Pheochromocytoma With Rapid Cyclic Blood Pressure Fluctuations: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Cyclic blood pressure fluctuations in pheochromocytoma are extremely rare, and previously reported cases have been limited to adults. We report a 5‐year‐old boy with von Hippel–Lindau disease and a left adrenal pheochromocytoma who developed rapid cyclic blood pressure fluctuations immediately after tracheal intubation.
Yamazaki K, Maeda C, Morikawa K, Okamoto N.   +3 more
europepmc   +2 more sources

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

Exploring vasopressin use in septic shock: a retrospective cohort study from Türkiye (VASCO-TURK)

BMC Anesthesiology
Background Vasopressin is a peptide hormone and often added to reduce catecholamine dose and side effects according to recent guidelines. Despite increasing global interest in vasopressin use in septic shock, real-world data from low- to middle-income ...
Ahmet Oğuzhan Küçük, Aleyna Bektaş Hocek, Davut Aydın, Berfin Acar, Ezgi Pehlivanlar, Mehtap Pehlivanlar Küçük   +5 more
doaj   +1 more source

Attention Based Optimization for 3D Shape Registration

Computer Graphics Forum, EarlyView.
Abstract Transformers are sequence‐to‐sequence architectures originally designed to handle structurally rigid and order‐sensitive data, such as text and images. At their core, they exploit the attention mechanism, which is permutation‐equivariant and relies on computing token‐to‐token relationships.
A. Riva, L. Olearo, S. Melzi
wiley   +1 more source

Semaglutide for Treating Paediatric Craniopharyngioma‐Related Obesity: A Multicentre Case Series

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Obesity is a complication of childhood craniopharyngioma that remains difficult to treat. We investigated whether semaglutide was associated with a decrease in BMI among adolescents with craniopharyngioma‐related obesity. Material and Methods This multicentre retrospective study included 20 patients < 18 years old with craniopharyngioma ...
Joanne Dornberger, Pascal Barat, Karine Aouchiche, Kevin Perge, Carine Villanueva, Sarah Castets, Natacha Bouhours‐Nouet, Aurelie Donzeau, Lucie Levaillant, Cecile Teinturier, Rachel Reynaud, Ahlam Azar‐Kolakez, Laetitia Martinerie, Dulanjalee Kariyawasam, Regis Coutant   +14 more
wiley   +1 more source

Influence of carbonate apatite nanoparticles incorporated into commercial dental adhesives on immediate and long‐term microtensile bond strength

European Journal of Oral Sciences, EarlyView.
Abstract This study assessed whether integrating carbonate apatite nanoparticles with a CO3/PO4 molar ratio of 5 (CA5n) into commercial adhesives affected the immediate or the long‐term microtensile bond strength (µTBS) between composite resin and dentin.
Heba E. AbdelRazik, Jon E. Dahl, Mina Aker Sagen   +2 more
wiley   +1 more source

A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination

The FEBS Journal, EarlyView.
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam, Tadtarit Anujareewat, Wachirawit Chinantuya, Pratchaya Watthaisong, Chayasith Uttamapinant, Somchart Maenpuen, Ruchanok Tinikul   +6 more
wiley   +1 more source