Results 261 to 270 of about 116,743 (338)

Price Discovery and Efficiency in Uniswap Liquidity Pools

open access: yesJournal of Futures Markets, Volume 45, Issue 8, Page 1023-1048, August 2025.
ABSTRACT Using almost three years of minute‐level data, we show that the efficiency of Uniswap v3 is much improved relative to v2, and some v3 pools are approaching or even exceeding Bitstamp in terms of price discovery ability. Regression results suggest that the channels of influence for these improvements are an increase in informed liquidity ...
Carol Alexander   +3 more
wiley   +1 more source

Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 8, Page 1314-1329, August 2025.
Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar   +2 more
wiley   +1 more source

Perioperative Mechanical Circulatory Support for Cardiac Assistance in Thoracic Surgery: A Scoping Review

open access: yesArtificial Organs, Volume 49, Issue 8, Page 1249-1264, August 2025.
High‐risk cardiac patients may benefit from timely temporary mechanical circulatory support (tMCS) implantation to provide perioperative hemodynamic stabilization and circulatory support, thus enabling them to undergo life‐saving thoracic surgery. CPB: cardiopulmonary bypass; IABP: intra‐aortic balloon pump; tMCS: temporary mechanical circulatory ...
Viviana Teresa Agosta   +4 more
wiley   +1 more source

Endotoxin hemoadsorption in refractory septic shock with multiorgan dysfunction and extreme endotoxin activity. [PDF]

open access: yesCrit Care
Ruiz-Rodríguez JC   +10 more
europepmc   +1 more source

Advancing antihypertensive drug development

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 15, Page 3389-3410, August 2025.
Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu   +5 more
wiley   +1 more source

Vasoactive-inotropic agents in pediatric patients undergoing cardiac surgery: A single-center retrospective study. [PDF]

open access: yesMedicine (Baltimore)
Sun YT   +3 more
europepmc   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 16, Page 3695-3709, August 2025.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio   +5 more
wiley   +1 more source

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