Results 51 to 60 of about 75,969 (306)

A Modular Biosensor Platform for the Detection of Plastic Monomers and the Engineering of Promiscuous Amidases Toward Challenging Substrates

Advanced Science, EarlyView.
A luciferase is used as biosensor for aldehydes, produced enzymatically from different monomeric building blocks of plastics like polyurethanes (PUs). The screening platform is used to monitor esterase, amidase, and urethanase activity and to guide the selection of enzyme variants with improved hydrolytic activities toward difficult to hydrolyze ...
Ina Somvilla, Hannah Meier, Florian Oehlschläger, Hannes Meinert, Lena Koch, Patrick Ihrle, Katharina M. Mehnert, Morten Flieger, Jonas Boß, Marco Seifert, Dominique Böttcher, Uwe T. Bornscheuer, Thomas Bayer   +12 more
wiley   +1 more source

Reticular Chemistry: A Versatile Platform for Engineering Heterogenous Biocatalysts

Advanced Science, EarlyView.
Rational design of reticular‐based heterogeneous biocatalysts enables significant enhancement in enzyme activity recovery and even achieves catalytic performance beyond native enzymes. Abstract Reticular materials, including metal‐organic frameworks (MOFs), covalent organic frameworks (COFs), and hydrogen‐bonded organic frameworks (HOFs), have emerged ...
Si Liu, Peiji Deng, Qianfan Chen, Qijun Sun, Yanhan Wang, Hongyu Shi, Kang Liang   +6 more
wiley   +1 more source

Piezoelectric Origami Metamaterials for Enhanced Handwriting Recognition and Trajectory Tracking

Advanced Intelligent Discovery, EarlyView.
This study introduces origami metamaterials inspired by Kresling piezoelectric generators to enhance biometric authentication and handwriting trajectory recognition. Overcoming sensor limitations in conventional devices, the design enables multichannel data acquisition with fewer sensors, utilizing machine learning to accurately identify content ...
Yinzhi Jin, Ting Tan, Zhimiao Yan
wiley   +1 more source

Associations between oxytocin and vasopressin concentrations, traumatic event exposure and posttraumatic stress disorder symptoms: group comparisons, correlations, and courses during an internet-based cognitive-behavioural treatment

European Journal of Psychotraumatology, 2021
Background: Posttraumatic stress disorder (PTSD) is characterized by impairments in extinction learning and social behaviour, which are targeted by trauma-focused cognitive behavioural treatment (TF-CBT).
Sinha Engel, Sarah Schumacher, Helen Niemeyer, Annika Kuester, Sebastian Burchert, Hannah Klusmann, Heinrich Rau, Gerd-Dieter Willmund, Christine Knaevelsrud   +8 more
doaj   +1 more source

Incidence of hyponatremia with vasopressin exposure in critically ill pediatric patients for postoperative cardiac support and shock management: A single-center, retrospective, case–control study

Journal of Pediatric Critical Care
Background: Vasopressin is used adjunctively to catecholamines for cardiovascular support but may be associated with hyponatremia. The objective of this study was to investigate the incidence of hyponatremia in critically ill pediatric patients receiving
Gustavo R. Alvira-Arill, Nian S. Chang, Helen Y. Lee, Nicole Tomas, Sharmeen Y. Roy, Balagangadhar R. Totapally   +5 more
doaj   +1 more source

Vasopressin and Terlipressin in the Treatment of Vasodilatory Septic Shock: A Systematic Review

Proceedings of Singapore Healthcare, 2011
Background: Vasodilatory septic shock unresponsive to fluid resuscitation requires the addition of vasopressors. Catecholamines remain the first line vasopressor therapy, but treatment failure is a potential problem.
Jie Lin Soong BSc (Pharm) (Hons), Wai Hing Lim B Pharm (Hons), M Clin Pharm   +1 more
doaj   +1 more source

Industrial strategies to minimize glycerol formation in ethanol fermentation by conventional Saccharomyces cerevisiae

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Industrial ethanol production faces the challenge of balancing metabolic efficiency with the minimization of byproducts such as glycerol, whose formation is intensified by osmotic, thermal, oxidative, and nutritional stresses. In the literature, two main approaches stand out for modulating its synthesis: the use of genetically modified strains
Lorena M. F. Leite, Silvio R. Andrietta, Telma T. Franco   +2 more
wiley   +1 more source

Vasopressin–aquaporin-2 pathway: recent advances in understanding water balance disorders [version 1; referees: 3 approved]

F1000Research, 2019
The alteration of water balance and related disorders has emerged as being strictly linked to the state of activation of the vasopressin–aquaporin-2 (vasopressin–AQP2) pathway.
Marianna Ranieri, Annarita Di Mise, Grazia Tamma, Giovanna Valenti   +3 more
doaj   +1 more source

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

Carbon Energy, EarlyView.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian, Tiantian Chai, Chunlei Zhao, Xiulai Chen   +3 more
wiley   +1 more source

DSOK‐0011 Potentially Regulates Circadian Misalignment and Affects Gut Microbiota Composition in Activity‐Based Anorexia Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a metabolic‐psychiatric disorder characterized by severe weight loss, hypercortisolemia, and hypothalamic–pituitary–adrenal (HPA) axis activation. In this study, we investigated the effect of inhibiting cortisol regeneration via the enzyme 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) on the ...
Hiroki Kawai, Nanami Wada, Shinji Sakamoto, Kenji Miyazaki, Taro Kato, Yoshihiro Horiuchi, Hiroshi Kirii, Hoang Duy Nguyen, Kenji Hinotsu, Yoshio Ohya, Takahiro Asada, Akiyoshi Yokode, Yuko Okahisa, Haruko Miyazaki, Toshitaka Oohashi, Manabu Takaki   +15 more
wiley   +1 more source