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Natural Peptide Toxins as an Option for Renewed Treatment of Type 2 Vasopressin Receptor-Related Diseases [PDF]

open access: yesBiology, 2023
The type 2 vasopressin receptor (V2R) is expressed in the kidneys, and it is the keystone of water homeostasis. Under the control of the antidiuretic hormone vasopressin, the V2R ensures vital functions, and any disturbance has dramatic consequences ...
Nicolas Gilles
doaj   +2 more sources

V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology [PDF]

open access: yesFrontiers in Endocrinology, 2023
The diluting and concentrating function of the kidney plays a crucial role in regulating the water homeostasis of the body. This function is regulated by the antidiuretic hormone, arginine vasopressin through the type 2 vasopressin receptor (V2R ...
László Sándor Erdélyi   +4 more
doaj   +2 more sources

Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones [PDF]

open access: yesFrontiers in Pharmacology, 2022
The urine concentrating function of the kidney is essential to maintain the water homeostasis of the human body. It is mainly regulated by the arginine-vasopressin (AVP), which targets the type 2 vasopressin receptor (V2R) in the kidney. The inability of
Laura Szalai   +17 more
doaj   +2 more sources

Vasopressin V2 receptor antagonists [PDF]

open access: bronzeCardiovascular Research, 2001
Hyponatremia due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and disorders of water retention such as congestive heart failure and cirrhosis is a common problem encountered in the care of the medical patient. Thus far, available treatment modalities for disorders of excess arginine vasopressin (AVP) secretion or action have ...
L L, Wong, J G, Verbalis
openaire   +3 more sources

Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]

open access: green, 2014
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
core   +3 more sources

Oxytocin and Vasopressin: Linking Pituitary Neuropeptides and their Receptors to Social Neurocircuits [PDF]

open access: goldFrontiers in Neuroscience, 2015
Oxytocin and vasopressin are pituitary neuropeptides that have been shown to affect social processes in mammals. There is growing interest in these molecules and their receptors as potential precipitants of, and/or treatments for, social deficits in ...
Danielle Andrea Baribeau   +1 more
doaj   +2 more sources

Partial nephrogenic diabetes insipidus with a novel arginine vasopressin receptor 2 gene variant. [PDF]

open access: diamondClin Pediatr Endocrinol, 2022
Ishida A   +6 more
europepmc   +3 more sources

Vasopressin Receptor Antagonists in Hyponatremia: Uses and Misuses [PDF]

open access: yesFrontiers in Medicine, 2017
Decreases in the concentration of sodium in plasma constitute hyponatremia, the commonest electrolyte disorder in clinical medicine. It is now well established that its presence conveys an increased mortality risk even when the decrement is mild.
Helbert Rondon-Berrios, Tomas Berl
doaj   +2 more sources

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