Results 91 to 100 of about 69,857 (321)

Inter‐Individual Differences in T1, T2, and Proton Density Using Quantitative Synthetic Imaging for 1H‐MRS Quantification

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Metabolite concentrations can be determined from proton magnetic resonance spectroscopy (1H‐MRS) data using water as an internal reference. This calculation requires tissue‐specific water T1 and T2 relaxation constants and proton density (PD).
Samantha A. Leech   +4 more
wiley   +1 more source

Hyponatremia and Congestive Heart Failure: A Marker of Increased Mortality and a Target for Therapy

open access: yesInternational Journal of Nephrology, 2011
Heart failure is one of the most common chronic medical conditions in the developed world. It is characterized by neurohormonal activation of multiple systems that can lead to clinical deterioration and significant morbidity and mortality. In this regard,
Adam Romanovsky   +2 more
doaj   +1 more source

A gut-to-brain signal of fluid osmolarity controls thirst satiation. [PDF]

open access: yes, 2019
Satiation is the process by which eating and drinking reduce appetite. For thirst, oropharyngeal cues have a critical role in driving satiation by reporting to the brain the volume of fluid that has been ingested1-12.
Ahn, Jamie S   +11 more
core   +1 more source

Smart molecular design for functional cellulose gels and flexible devices

open access: yesSmart Molecules, EarlyView.
This review systematically outlines the performance enhancement of cellulose gels, presenting optimization strategies across molecular, supramolecular, and macroscopic scales. It discusses advanced approaches to improve their mechanical, electrical, and thermal properties, and highlights promising applications in flexible robotics, electric devices, e ...
Zeshi Li   +6 more
wiley   +1 more source

New Topics in Vasopressin Receptors and Approach to Novel Drugs: Effects of Vasopressin Receptor on Regulations of Hormone Secretion and Metabolisms of Glucose, Fat, and Protein

open access: yesJournal of Pharmacological Sciences, 2009
The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion.
Akito Tanoue
doaj   +1 more source

Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor [PDF]

open access: yes, 2007
More than 70 missense mutations have been identified in the human melanocortin 4 receptor (MC4R), and many of them have been associated with obesity. In a number of cases, the causal link between mutations in MC4R and obesity is controversially discussed.
Annette Grüters   +34 more
core   +1 more source

Mannose Oligosaccharide‐Conjugated In Situ Pore‐Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles

open access: yesSmall Methods, EarlyView.
Design of an injectable porous hydrogel modulating macrophages and their secreted EVs for joint defect repair in the pathology of rheumatoid arthritis. a) The solution containing HA and CS‐MOS, upon mixing with a crosslinker solution, undergoes porous hydrogel formation with the escape of generated CO₂ gas.
Anan Zhang   +9 more
wiley   +1 more source

Maternal glucocorticoids have persistent effects on offspring social phenotype irrespective of opportunity for social buffering

open access: yesJournal of Animal Ecology, EarlyView.
This study tests whether early‐life maternal association buffers offspring from the effects of prenatal stress in a facultatively social lizard. Despite clear effects of maternal glucocorticoids on growth and social behaviour, social associations did not mitigate these effects, revealing limits to social buffering in this species.
Kirsty J. MacLeod   +4 more
wiley   +1 more source

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus   +2 more
wiley   +1 more source

Loanwords and Linguistic Phylogenetics: *pelek̑u‐ ‘axe’ and *(H)a(i̯)g̑‐ ‘goat’1

open access: yesTransactions of the Philological Society, Volume 123, Issue 1, Page 116-136, March 2025.
Abstract This paper assesses the role of borrowings in two different approaches to linguistic phylogenetics: Traditional qualitative analyses of lexemes, and quantitative computational analysis of cognacy. It problematises the assumption that loanwords can be excluded altogether from datasets of lexical cognacy.
Simon Poulsen
wiley   +1 more source

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