Results 101 to 110 of about 69,857 (321)

A receptor-based analysis of local ecosystems in the human brain. [PDF]

, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source

Vasopressin receptor-mediated endocytosis in cells transfected with V1-type vasopressin receptors

Kidney International, 1993
We examined the process of receptor-mediated endocytosis in A-9 lung fibroblast and chinese hamster ovary (CHO) cells transfected with the recently cloned vasopressin V1a receptor (51). We used a fluorescent labeled vasopressin analog (rhodamine-mercaptopropionic acid lysine vasopressin) and radiolabeled vasopressin to examine this process in the two ...
Lutz, W, Sanders, M, Salisbury, J, Lolait, SJ, O'Carroll, A-M, Kumar, R   +5 more
openaire   +2 more sources

Rare but relevant: MDMA and hyponatraemia

Addiction, EarlyView.
Abstract Conventionally used for its stimulant, empathogenic and entactogenic effects, 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most commonly used psychoactive drugs, specifically among young adults and in nightlife and recreational party contexts.
Maria Rita Garcia, Nelson G. M. Gomes, Diana Dias‐da‐Silva   +2 more
wiley   +1 more source

DINeR: Database for Insect Neuropeptide Research [PDF]

, 2017
Neuropeptides are responsible for regulating a variety of functions, including development, metabolism, water and ion homeostasis, and as neuromodulators in circuits of the central nervous system.
Davies, Shireen-Anne, Dow, Julian, Nässel, Dick R., Pandit, Aniruddha A., Yeoh, Joseph G.C., Zandawala, Meet   +5 more
core   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

In vitro binding and receptor-mediated activity of terlipressin at vasopressin receptors V1 and V2

Journal of Experimental Pharmacology, 2017
Khurram Jamil,1 Stephen Chris Pappas,2 Krishna R Devarakonda1 1Clinical Development, Mallinckrodt Pharmaceuticals, Bedminster, 2Orphan Therapeutics, LLC, Lebanon, NJ, USA Abstract: Terlipressin, a synthetic, systemic vasoconstrictor with selective ...
Jamil K, Pappas SC, Devarakonda KR
doaj  

A Rare Case of Congenital Diabetes Insipidus

Frontiers in Medicine, 2015
Congenital nephrogenic diabetes insipidus (NDI) is a conformation disease resulting from protein misfolding. Ninety percent of mutations result from the inactivating mutations of the arginine vasopressin receptor 2 (AVPR2) gene transmitted in an X-linked
Tanvi eRege, Srujana ePolsani, Belinda eJim   +2 more
doaj   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

Andrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández, Ferran Garriga, Adeel Ahmad, Lorena Padilla, Carolina Maside, Sergi Bonet, Isabel Barranco, Jordi Roca, Luis Miguel Pastor, Marc Yeste   +9 more
wiley   +1 more source

Continuous growth of proximal tubular kidney epithelial cells in hormone-supplemented serum-free medium. [PDF]

, 1982
An epithelial cell line from pig kidney (LLC-PK1) with properties of proximal tubular cells can be maintained indefinitely in hormone-supplemented serum-free medium. Continuous growth requires the presence of seven factors: transferrin, insulin, selenium,
Chuman, L, Cohen, AH, Fine, LG, Saier, MH   +3 more
core  

Modeling Autistic Features in Animals [PDF]

, 2011
A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication.
Patterson, Paul H.
core   +1 more source