Results 111 to 120 of about 69,857 (321)

Differential Impact of Polymyxin B Hemadsorption on Long‐Term Mortality in Septic Shock: A Retrospective Analysis of Intra‐Abdominal Versus Extra‐Abdominal Infections

Artificial Organs, EarlyView.
In this single‐center retrospective cohort study, the use of PMX‐HA was significantly associated with a reduced risk of 1‐year mortality in patients with septic shock due to intra‐abdominal infection. In contrast, no significant association was observed between PMX‐HA use and 1‐year mortality risk in patients with septic shock caused by extra‐abdominal
Tomoki Tanaka, Kazunori Fujino, Yasuyuki Tsujita, Yugo Matsumoto, Mitsuhiro Fujino, Hidemitsu Miyatake, Naoto Mizumura, Junji Shimizu, Takuma Kishimoto, Naoto Shiomi   +9 more
wiley   +1 more source

Lack of vasopressin receptors in liver, but not in kidney, of ob/ob mice [PDF]

, 1983
F. Assimacopoulos‐Jeannet, B. Cantau, G van de Werve, Serge Jard, B. Jeanrenaud   +4 more
openalex   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model

Cell Reports Medicine
Summary: Confronting oxytocin and vasopressin deficits in autism spectrum disorders and rare syndromes brought promises and disappointments for the treatment of social disabilities.
Amélie M. Borie, Yann Dromard, Prabahan Chakraborty, Pierre Fontanaud, Emilie M. Andre, Amaury François, Pascal Colson, Françoise Muscatelli, Gilles Guillon, Michel G. Desarménien, Freddy Jeanneteau   +10 more
doaj   +1 more source

Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex [PDF]

, 2022
Julien Bous, Aurélien Fouillen, Hélène Orcel, Stefano Trapani, Xiaojing Cong, Simon Fontanel, Julie Saint‐Paul, Joséphine Lai‐Kee‐Him, Serge Urbach, Nathalie Sibille, Rémy Sounier, Sébastien Granier, Bernard Mouillac, Patrick Bron   +13 more
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Roles of vasopressin in renal blood flow and vascular resistance in male mice after treadmill running: A mechanism for ALPE

Physiological Reports
Acute renal failure with severe loin pain and patchy renal ischemia after high‐intensity exercise (ALPE) is a rare form of acute kidney injury. This study examined the role of vasopressin and its receptor, AVPR1A, in ALPE using a mouse model of brief ...
Kazutoshi Nomura, Mamoru Tanida, Ryoko Akai, Tomohisa Yabe, Ai Fujii, Kanae Nomura, Keiichiro Okada, Kazuaki Okino, Norifumi Hayashi, Keiji Fujimoto, Yasutaka Kurata, Takao Iwawaki, Kengo Furuichi   +12 more
doaj   +1 more source

Association between arginine vasopressin receptor 1A (AVPR1A) polymorphism and inequity aversion. [PDF]

Proc Biol Sci, 2023
Tanaka H, Nishina K, Shou Q, Takahashi H, Sakagami M, Matsuda T, Inoue-Murayama M, Takagishi H.   +7 more
europepmc   +1 more source

Molecular Aspect of Annelid Neuroendocrine system

, 2007
Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source