Results 11 to 20 of about 69,857 (321)
A Novel V1a Receptor Antagonist Blocks Vasopressin-induced Changes in the CNS Response to Emotional Stimuli: an fMRI Study [PDF]
Frontiers in Systems Neuroscience, 2013 Background: We hypothesized that RX246, a vasopressin V1a receptor antagonist, blocks the effect of intranasally administered vasopressin on brain processing of angry Ekman faces.
Royce J Lee +8 more
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Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V). [PDF]
, 2013 Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased
Armstrong, Stephen P +4 more
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Glucocorticoid Receptor Maintains Vasopressin Responses in Kidney Collecting Duct Cells
Frontiers in Physiology, 2022 Water permeability of the kidney collecting ducts is regulated in part by the amount of the molecular water channel protein aquaporin-2 (AQP2), whose expression, in turn, is regulated by the pituitary peptide hormone vasopressin.
Hsiu-Hui Yang +5 more
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Frontiers in Physiology, 2021 Water permeability of the kidney collecting ducts is regulated by the peptide hormone vasopressin. Between minutes and hours (short-term), vasopressin induces trafficking of the water channel protein aquaporin-2 to the apical plasma membrane of the ...
Cheng-Hsuan Ho +4 more
doaj +1 more source
Apelin and Vasopressin: The Yin and Yang of Water Balance
Frontiers in Endocrinology, 2021 Apelin, a (neuro)vasoactive peptide, plays a prominent role in controlling body fluid homeostasis and cardiovascular functions. Experimental data performed in rodents have shown that apelin has an aquaretic effect via its central and renal actions.
Pierre-Emmanuel Girault-Sotias +4 more
doaj +1 more source
Vasopressin receptor antagonists [PDF]
Kidney International, 2006 The first non-peptide vasopressin receptor antagonist (VRA) was recently approved by the United States Food and Drug Administration, and several others are now in late stages of clinical development. Phase 3 trials indicate that these agents predictably reduce urine osmolality, increase electrolyte-free water excretion, and raise serum sodium ...
Greenberg, A., Verbalis, J.G.
openaire +2 more sources
AVP-induced increase in AQP2 and p-AQP2 is blunted in heart failure during cardiac remodeling and is associated with decreased AT1R abundance in rat kidney. [PDF]
PLoS ONE, 2015 The objective was to examine the renal effects of long-term increased angiotensin II and vasopressin plasma levels in early-stage heart failure (HF). We investigated the regulations of the V2 vasopressin receptor, the type 1A angiotensin II receptor, the
Sophie Constantin Lütken +2 more
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Biomedicines, 2021 Vasopressins are evolutionarily conserved peptide hormones. Mammalian vasopressin functions systemically as an antidiuretic and regulator of blood and cardiac flow essential for adapting to terrestrial environments.
Samantha Sparapani +72 more
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The Journal of Headache and Pain, 2022 Background Hypothalamus is a key region in migraine attacks. In addition, women are disproportionately affected by migraine. The calcitonin gene-related peptide (CGRP) system is an important key player in migraine pathophysiology. CGRP signaling could be
Aida Maddahi +2 more
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Frontiers in Endocrinology, 2022 The neuronal and neuroendocrine peptides oxytocin (OT) and vasotocin (VT), including vasopressins, have six cognate receptors encoded by six receptor subtype genes in jawed vertebrates. The peptides elicit a broad range of responses that are specifically
Daniel Ocampo Daza +3 more
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