We demonstrate rapid, sensitive detection of key blood metabolites using an 80 MHz low‐field NMR spectrometer, benchmarking signal‐to‐noise ratios and acquisition efficiency across experimental designs. Millimolar metabolites such as glucose and lactate are reliably detected and quantified within seconds, while simulation‐assisted spectral fitting ...
Alexander D. Hill +4 more
wiley +1 more source
Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice. [PDF]
Harada K +10 more
europepmc +1 more source
Functional characterization of a loss-of-function mutant I324M of arginine vasopressin receptor 2 in X-linked nephrogenic diabetes insipidus. [PDF]
Wang L +7 more
europepmc +1 more source
Deceptive beauty of non‐natural structures
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich +1 more
wiley +1 more source
Activation of arginine vasopressin receptor 1a reduces inhibitory synaptic currents at reciprocal synapses in the mouse accessory olfactory bulb. [PDF]
Taniguchi M +3 more
europepmc +1 more source
Recanting Twins: Addressing Intermediate Confounding in Mediation Analysis
ABSTRACT The presence of intermediate confounders, also called recanting witnesses, is a fundamental challenge to the investigation of causal mechanisms in mediation analysis, preventing the identification of natural path‐specific effects. Common alternatives (such as randomizational interventional effects) are problematic because they can take non ...
Tat‐Thang Vo +4 more
wiley +1 more source
The Vasopressin Receptor Antagonist Tolvaptan Counteracts Tumor Growth in a Murine Xenograft Model of Small Cell Lung Cancer. [PDF]
Naldi L +9 more
europepmc +1 more source
A snake toxin as a theranostic agent for the type 2 vasopressin receptor. [PDF]
Droctové L +20 more
europepmc +1 more source
The novel vasopressin receptor (V1aR) antagonist SRX246 reduces anxiety in an experimental model in humans: a randomized proof-of-concept study. [PDF]
Lago TR +12 more
europepmc +1 more source
Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus [PDF]
Larry S. Barak +3 more
openalex +1 more source

