Results 211 to 220 of about 69,857 (321)

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Subcutaneous therapy for portal hypertension: PHIN-214, a partial vasopressin receptor 1A agonist. [PDF]

Biomed Pharmacother
Castillo GM, Yao Y, Guerra RE, Jiang H, Nishimoto-Ashfield A, Lyubimov AV, Alfaro JF, Striker KA, Buynov N, Schwabl P, Bolotin EM.   +10 more
europepmc   +1 more source

Molecular cloning and functional characterization of V₂ [8-Iysine] vasopressin and oxytocin receptors from a pig kidney cell line (LLC-PK1)

, 1993
Gorboulev, Valentin, Büchner, Hubert, Akhundova, Aida, Fahrenholz, Falk   +3 more
openalex   +1 more source

Intraoperative Use of Vasoactive Agents in Non‐Cardiac Surgery: Protocol for a Post Hoc Cohort Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 2, February 2026.
ABSTRACT Background Intraoperative hypotension is a well‐known clinical condition and often treated with vasoactive agents. Previous cohort studies have indicated that large numbers of patients receive this treatment, but they have been limited to specific surgical populations or single agents.
Emilie Stokholm Bækgaard, Morten Vester‐Andersen, Anders Granholm, Morten Hylander Møller, Ben Creagh‐Brown, Ib Jammer, Mette Krag   +6 more
wiley   +1 more source

Guanine nucleotide regulation of [3H]vasopressin binding to liver plasma membranes and solubilized receptors Evidence for the involvement of a guanine nucleotide regulatory protein [PDF]

, 1986
Dejan Bojanic, John N. Fain
openalex   +1 more source

Tolvaptan, a vasopressin V₂ receptor antagonist, is the world’s first approved drug for treatment of autosomal dominant polycystic kidney disease (ADPKD)

, 2021
Yoshihisa Yamada, Hiroyuki Fujiki, Hiroshi Mizuguchi, Yukinobu Takeshita, Katsuji Hattori, Koji Ohmoto, Miki Aihara, Keisuke Nagano, Yoshitaka Yamamura   +8 more
openalex   +2 more sources

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, Volume 59, Issue 2, February 2026.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

Normothermia Machine Perfusion Is Associated With Reduced Transfusion Requirements, Improved Hemodynamic Stability, and Decreased Vasopressor Use During the Postreperfusion Phase of Liver Transplantation

Clinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Background Normothermic machine perfusion (NMP) has emerged as a valuable preservation technique, expanding the donor pool and improving clinical outcomes in liver transplantation (LT). Despite its growing adoption and reported advantages, the perioperative impact of NMP remains incompletely defined.
Xian Zhao, Samer Ebaid, Nickolas Feduska, Christian Park, Fady Kaldas, Christopher Wray, Victor W. Xia   +6 more
wiley   +1 more source

D1/D5 receptor activation promotes long‐term potentiation and synaptic tagging/capture in hippocampal area CA2

The FEBS Journal, Volume 293, Issue 3, Page 766-780, February 2026.
Activation of dopamine receptor D1 (D1R) stimulates PKA and ERK pathways via dissociation of stimulatory and olfactory G protein alpha subunits (Gαs/olf). PKA relieves striatal‐enriched protein tyrosine phosphatase (STEP) inhibition of ERK, promoting cyclic adenosine monophosphate response element‐binding protein (CREB)‐driven transcription of ...
Kevin Chua, Yee Song Chong, Sreedharan Sajikumar   +2 more
wiley   +1 more source

Comparisons of the socio-behavioral differences between chimpanzees (Pan troglodytes) and bonobos (Pan paniscus), investigating the impact of a naturally occurring polymorphic microsatellite deletion in the 5’ flanking region of arginine vasopressin receptor 1a (AVPR1a) on gene expression and sociality within the Pan genus

, 2016
R. E. Evans
openalex   +1 more source