Results 101 to 110 of about 25,436 (310)

Percutaneous mechanical circulatory support for acute right heart failure: A practical approach

open access: yesESC Heart Failure, EarlyView.
This is an overview of percutaneous mechanical circulatory support options for acute right heart failure, illustrating key clinical scenarios, device types, and principles of tailored device selection based on haemodynamics and underlying pathology. Abstract Acute right heart failure (RHF) represents a critical entity with significant morbidity and ...
Mario Gramegna   +18 more
wiley   +1 more source

Degradation Pathways of Therapeutic Peptides in Aqueous Solutions and Strategies to Improve Stability [PDF]

open access: yes, 2015
A number of hormones, enzymes, antitumor agents, antibiotics and neurotransmitters are peptides. Nowadays, peptides are used as therapeutic agents against diverse disease areas such as neurological, endocrinological and hematological disorders ...
Avanti, Christina
core  

New cardiovascular biomarkers in patients with advanced cancer – A prospective study comparing MR‐proADM, MR‐proANP, copeptin, high‐sensitivity troponin T and NT‐proBNP

open access: yesEuropean Journal of Heart Failure, EarlyView.
(A) Univariable receiver operating characteristic (ROC) curves for all biomarkers. (B) Kaplan–Meier curves for best cut‐point of mid‐regional pro‐adrenomedullin (MR‐proADM) for survival (n = 442). AUC, area under the curve; CI, confidence interval; HR, hazard ratio; hsTnT, high‐sensitivity troponin T; MR‐proANP, mid‐regional pro‐atrial natriuretic ...
Markus S. Anker   +18 more
wiley   +1 more source

Challenges in Management of Mesenteric Ischemia: Review [PDF]

open access: yes
Mesenteric ischemia is a complex disease characterized by insufficient blood supply to the mesentery and, therefore, the intestinal tissue, which continues to confuse doctors. Despite its low frequency, consistent clinical manifestations of pathology and
Naser, Maged   +2 more
core   +2 more sources

Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

open access: yesEuropean Journal of Heart Failure, EarlyView.
Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, rate ratio. Abstract Aims The efficacy and safety of the non‐steroidal mineralocorticoid receptor antagonist, finerenone, have not been examined in patients
Jawad H. Butt   +18 more
wiley   +1 more source

Leu8 and Pro8 oxytocin agonism differs across human, macaque, and marmoset vasopressin 1a receptors [PDF]

open access: yes, 2019
Oxytocin (OXT) is an important neuromodulator of social behaviors via activation of both oxytocin receptors (OXTR) and vasopressin (AVP) 1a receptors (AVPR1a).
French, Jeffrey A.   +4 more
core   +1 more source

Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

open access: yesEuropean Journal of Heart Failure, EarlyView.
The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.
Jawad H. Butt   +16 more
wiley   +1 more source

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