Results 251 to 260 of about 71,436 (315)
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Synthesis of O-alkylated lysine-vasopressins, inhibitors of the antidiuretic response to lysine-vasopressin.

Journal of Medicinal Chemistry, 1978
[Mpa1,Tyr(Et)2]-LVP (1-deamino-2-O-ethyltyrosine-8-lysine-vasopressin), [Mpa1,Tyr(n-Pr)2]-LVP, [Tyr(n-Bu)2]-LVP, [Mpa1,Tyr(n-Bu)2]-LVP, and [Mpa1,Tyr(n-hexyl)2]-LVP were synthesized in solution by the p-nitrophenyl ester method.
L. Larsson   +3 more
semanticscholar   +1 more source

Vasopressin and vasopressin receptors in brain edema

2020
Vasopressin is a peptide hormone produced in the hypothalamus and released from the posterior pituitary. Secretion of vasopressin is followed by activation of its receptors V1a, V1b, and V2 throughout the body. Each receptor type is responsible for a specific function of vasopressin.
J Paul Elliott   +2 more
openaire   +2 more sources

The antidiuretic potency of arginine and lysine vasopressins in the pig with observations on porcine renal function.

Endocrinology, 1958
In the dog intravenous arginine vasopressin is a much more potent anti-diuretic agentin terms of its vasopressor activity than lysine vasopressin. Ar-ginine vasopressin appears to be the antidiuretic hormone of the dog and many other mammals whereas ...
R. Munsick   +2 more
semanticscholar   +1 more source

Biosynthesis of Vasopressin

Journal of Cardiovascular Pharmacology, 1986
The nonapeptide vasopressin is synthetized as part of a longer common precursor polypeptide, together with its carrier protein neurophysin and a glycopeptide of unknown function. The gene for this common precursor has been isolated and sequenced and shown to comprise three exons encoding, respectively, the protein domains approximately corresponding to
Dietmar Richter   +2 more
openaire   +3 more sources

Vasopressin and Vasopressin Antagonists in Heart Failure

2017
Despite the introduction of multiple new pharmacological agents over the past three decades in the field of heart failure (HF), overall prognosis remains poor. Hyponatremia is prevalent in HF patients and has been suggested as a contributor to poor response to standard therapy.
Finn Gustafsson   +1 more
openaire   +3 more sources

Effect of magnesium ion on the response of the rat uterus to neurohypophysial hormones and analogues.

Endocrinology, 1960
Absolute oxytocic potencies of highly purified neurohypophysial hormones and analogues were determined on isolated rat uteri suspended in van Dyke-Hastings solution. Assays were performed in bath solutions with and without magnesium ions.
R. Munsick
semanticscholar   +1 more source

The use of corticotrophin production by adenohypophysial tissue in vitro for the detection and estimation of potential corticotrophin releasing factors.

Journal of Endocrinology, 1977
The cytochemical assay for ACTH has been adapted into a method for the detection and determination of potential corticotropsin releasing factors. Of the many putative transmitter substances tested, only the posterior pituitary polypeptides resembled ...
J. Buckingham, J. R. Hodges
semanticscholar   +1 more source

Vasopressin Receptors

Trends in Endocrinology & Metabolism, 2000
The biological effects of arginine vasopressin (AVP) are mediated by three receptor subtypes: the V1a and V1b receptors that activate phospholipases via Gq/11, and the V2 receptor that activates adenylyl cyclase by interacting with Gs. Isolation of the cDNAs encoding the V1a and V1b receptor subtypes explained the tissue variability of V1 antagonist ...
openaire   +3 more sources

Vasopressin antagonists

Cellular and Molecular Life Sciences, 2006
Effects of vasopressin via V1a- and V2-receptors are closely implicated in a variety of water-retaining diseases and cardiovascular diseases, including heart failure, hyponatraemia, hypertension, renal diseases, syndrome of inappropriate antidiuretic hormone secretion, cirrhosis and ocular hypertension.
Lemmens, Rosa, Kamyar, Majid-Reza
openaire   +2 more sources

Vasopressin receptor-mediated endocytosis: current view.

American Journal of Physiology, 1991
A number of peptide hormones have been shown to undergo receptor-mediated endocytosis (RME). RME involves the internalization of receptor-ligand complexes followed by delivery to an intracellular compartment, the endosome, from which ligands or receptors
W. Lutz, J. Salisbury, R. Kumar
semanticscholar   +1 more source

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