Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó+1 more
wiley +1 more source
Increased copeptin may reflect vasopressin-related metabolic changes after bariatric surgery. [PDF]
Galbiati F+7 more
europepmc +1 more source
The response of the hepatic artery blood flow to the intra-celiac infusion of vasopressin as monitored with electromagnetic flow probes [PDF]
Fingeroth, Richard Jay
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Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise
Abstract figure legend This study unveiled the essential role of the orexinergic nervous system in the central circuitry that transmits central command signals for locomotor exercise. We observed the excitation of orexinergic neurons by voluntary locomotor exercise in rats.
Emi Narai+7 more
wiley +1 more source
Restoration of suppressed baroreflex sensitivity in rats with hereditary diabetes insipidus (Brattleboro rats) by arginine- vasopressin and DDAVP [PDF]
Imai Yutaka+2 more
core +1 more source
Abstract figure legend Schematic diagram of intestinal nerve abnormality underlying the mechanisms of visceral hypersensitivity. In physiological conditions with normal sensation, enteric neurons are situated in the submucosal and myenteric plexuses, and the spinal afferent fibres ramify within the enteric plexus. However, serotonin/5‐hydroxytryptamine
Tzu‐Yi Lee+9 more
wiley +1 more source
Oxytocin, but not vasopressin, decreases willingness to harm others by promoting moral emotions of guilt and shame. [PDF]
Zheng X+7 more
europepmc +1 more source
Management Strategies for Refractory Esophageal Varices
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
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Pharmacokinetic and pharmacodynamic evaluation of various vasopressin doses and routes of administration in a neonatal piglet model. [PDF]
Ramsie M+4 more
europepmc +1 more source
ABSTRACT Desmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics.
Sophie Hodin+7 more
wiley +1 more source