Control of Renal Tubular Sodium and Water Absorption - An Animated Model
The kidney is among the most complex of internal organs. This is due in large part to the multiple and integrated mechanisms of the kidney and their highly dynamic regulation by a variety of neurohormonal and hemodynamic inputs.
Jody Gookin+3 more
doaj +1 more source
Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv
Towards the convergent therapeutic potential of GPCRs in autism spectrum disorders [PDF]
Changes in genetic and/or environmental factors to developing neural circuits and subsequent synaptic functions are known to be a causative underlying the varied socio-emotional behavioural patterns associated with autism spectrum disorders (ASD). Seven transmembrane G protein-coupled receptors (GPCRs) comprising the largest family of cell-surface ...
arxiv
© 2015, © The Intensive Care Society 2015.Introduction: Septic shock is a life-threatening condition requiring vasopressor agents to support the circulatory system. Several agents exist with choice typically guided by the specific clinical scenario.
Gordon, AC+3 more
core +1 more source
COMPARISON OF VASOPRESSIN AND PHENYLEPHRINE IN TREATMENT OF DOPAMINE RESISTANT SEPTIC SHOCK – A RANDOMISED CONTROL TRIAL [PDF]
Objectives: Septic shock is associated with refractory hypotension and organ dysfunction and remains an important cause of mortality in intensive care units (ICUs). Vasopressors are the first-line treatment.
BISWAL, PRERNA+3 more
core +1 more source
Deep Breath Relaxation Training to Reduce Dysmenorrhoea Pain in Nursing Students, University of Muhammadiyah Gorontalo [PDF]
Dysmenorrhoea is one of the most common gynecological problems affecting more than 50% of women and causes an inability to perform daily activities for 1 to 3 days each month. One of the management of pain during menstruation is by relaxing deep breaths,
Muhamad, Zuriati, Yunus, Pipin
core +1 more source
Molecular evolution of the neurohypophysial hormone precursors in mammals: comparative genomics reveals novel mammalian oxytocin and vasopressin analogues [PDF]
Among vertebrates the neurohypophysial hormones show considerable variation. However, in eutherian mammals they have been considered rather conserved, with arginine vasopressin (AVP) and oxytocin (OT) in all species except pig and some relatives, where ...
Wallis, Michael
core +1 more source
A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new $β$-arrestin inhibitor [PDF]
$\beta$-arrestins play pivotal roles in seven transmembrane receptor (7TMR) signalling and trafficking. To study their functional role in the regulation of specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are available.
arxiv +1 more source
Vasopressin (antidiuretic hormone) is emerging as a potentially major advance in the treatment of a variety of shock states. Increasing interest in the clinical use of vasopressin has resulted from the recognition of its importance in the endogenous response to shock and from advances in understanding of its mechanism of action.
openaire +3 more sources
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im+10 more
wiley +1 more source