Results 91 to 100 of about 65,263 (290)
Epidemiology of invasive aspergillosis in critically ill patients : clinical presentation, underlying conditions, and outcome [PDF]
, 2015 Introduction: Invasive aspergillosis (IA) is a fungal infection that particularly affects immunocompromised hosts. Recently, several studies have indicated a high incidence of IA in intensive care unit (ICU) patients.
Blasco-Navalpotro, Miguel +13 more
core +3 more sources
Artificial Organs, EarlyView.Percutaneous femoro‐femoral V‐A ECMO cannulation was associated with more than a two‐fold lower risk of site bleeding and nearly a six‐fold lower risk of infection compared with surgical cut‐down, with no difference in limb ischemia. Absence of distal perfusion catheterization and larger arterial cannula size were additional modifiable ischemia risk ...
Axel Dimberg +3 more
wiley +1 more source
Neonatal Shock: Current Dilemmas and Future Research Avenues
ChildrenNeonatal shock presents a complex clinical challenge and is one of the leading causes of mortality. Traditionally, neonatal shock is equated to hypotension, and therapeutics are often initiated based on low blood pressure (BP) values alone. This fails to
Vijay Kumar Krishnegowda +3 more
doaj +1 more source
Artificial Organs, EarlyView.We report an insight from the PELS‐1– a multicentre, international registry focusing on postocardiotomy extracorporeal support use between 2000 and 2020. We focused on 24/2163 (1.1%) patients requiring V‐V ECMO after cardiac surgery. Mortality was high, with 21.7% of patients discharged alive and an overall 1‐year survival probability of 12.5 ...
Pasquale Nardelli +39 more
wiley +1 more source
Characterisation and Prognostic Implication of Cholestasis After Burn Injury
Alimentary Pharmacology &Therapeutics, EarlyView.In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler +16 more
wiley +1 more source
Extracorporeal membrane oxygenation improves survival in a novel 24-hour pig model of severe acute respiratory distress syndrome [PDF]
, 2016 Indexación: Web of Science; Pub Med CentralExtracorporeal membrane oxygenation (ECMO) is increasingly being used to treat severe acute respiratory distress syndrome (ARDS).
Alegría, Leyla +16 more
core
Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is a severe condition with a challenging diagnosis in the intensive care unit (ICU), for which current recommendations rely on fulfilling five of eight HLH‐2004 criteria.
Claire Queffeulou +4 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Flow‐controlled expiration (FLEX) has been shown to significantly enhance oxygenation in horses under laboratory conditions. Objective This study aims to corroborate these findings by evaluating the effects of FLEX on gas exchange in a randomised clinical trial involving a large population of clinical horses undergoing orthopaedic ...
Klaus Hopster +5 more
wiley +1 more source