Vasopressor therapy represents a key part of intensive care patient management, used to increase and maintain vascular tone and thus adequate tissue perfusion in patients with shock. Norepinephrine is the preferred first-line agent because of its reliable vasoconstrictor effects, with minimal impact on heart rate, and its mild inotropic effects ...
Jean-Louis Vincent, Filippo Annoni
openaire +2 more sources
Effect of intraoperative constant rate infusion of lidocaine on short-term survival of dogs with septic peritonitis: 75 cases (2007-2011) [PDF]
OBJECTIVE To investigate whether intraoperative administration of a lidocaine infusion to dogs with septic peritonitis was associated with short-term (48 hours) survival after surgery. DESIGN Retrospective case series.
Christopher J. Seymour+4 more
core +1 more source
Blood product transfusion in emergency department patients: A case-control study of practice patterns and impact on outcome [PDF]
Definitions of comorbid conditions.
Beyer, Alexander+4 more
core +3 more sources
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. [PDF]
OBJECTIVE: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012." DESIGN: A consensus committee of 55 international experts representing 25 international organizations was convened.
Alhazzani, W+58 more
core +5 more sources
Year in review in Intensive Care Medicine 2012. II: Pneumonia and infection, sepsis, coagulation, hemodynamics, cardiovascular and microcirculation, critical care organization, imaging, ethics and legal issues. [PDF]
Journal ArticleSCOPUS: re.jSCOPUS: re.jinfo:eu-repo/semantics ...
Antonelli, Massimo+18 more
core +2 more sources
Disease severity adversely affects delivery of dialysis in acute renal failure [PDF]
Background/Aims: Methods of intermittent hemodialysis (IHD) dose quantification in acute renal failure (ARF) are not well defined. This observational study was designed to evaluate the impact of disease activity on delivered single pool Kt/V-urea in ARF ...
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference+20 more
core +1 more source
Objective: This study aimed to investigate any association between vasopressor dose and mortality, and to identify factors independently associated with 28-day mortality in adult patients with septic shock.
Surat Tongyoo+4 more
doaj +1 more source
Levosimendan for the prevention of acute organ dysfunction in sepsis [PDF]
BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...
Al-Beidh, F+16 more
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The recent article by Wen et al., published in PLOS ONE, titled “Effects of neuraxial anesthesia in sitting and lateral positions on maternal hemodynamics in cesarean section: A systematic review and meta-analysis,” caught my attention.
Shanshan Wu
doaj +1 more source
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat+31 more
core +1 more source