Results 141 to 150 of about 12,305 (169)

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

A Hysteresis‐Based Framework for Evaluating and Selecting Streamflow Monitoring Approaches Under Unsteady Gradually Varied Flow Conditions

Water Resources Research, Volume 62, Issue 9, September 2026.
Abstract Streamflow estimates derived from stage–discharge rating curves (HQRC) inadequately represent the spatiotemporal complexity of unsteady gradually varied flows (UGVF) and are commonly reported without uncertainty, encouraging their treatment as deterministic.
M. Muste, K. Kim, D. Kim, I. Demir
wiley   +1 more source

Supraphysiological 25‐Hydroxyvitamin D3 and Calcipotriol Induce Reactive Oxygen Species, Mitochondrial Dysfunction and Apoptosis in HeLa Cervical Cancer Cells

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Supraphysiological 25(OH)D3 and calcipotriol induced ROS accumulation or redox disturbance, increased mitochondrial membrane depolarization, reduced antioxidant enzyme activity, and caused apoptotic cell death in HeLa cells. ABSTRACT Cervical cancer remains a major global health challenge, necessitating continued advances in therapeutic strategies ...
Hoi Ching Cherry Chan, Sachin Bhoora, Esther Zhou, Sumari Marais, Tahir S. Pillay, Rivak Punchoo   +5 more
wiley   +1 more source

Numerical experiments into optimisation of VDR filters

, 2007
A comprehensive model of the filtration process, that includes the effect of deposition on,head loss and removal efficiency, has been combined with a hydraulic model,of a Variable Declining Rate (VDR) plant.
Dąbrowski, Wojciech, Zielina, Michal, Mackie, R. Ian   +2 more
core   +1 more source

Prevalence of Vitamin D Deficiency and Its Association With PTH and Type 1 Diabetes Mellitus (T1DM) in a Multicultural Pediatric Population in the United Arab Emirates, 2023

Journal of Diabetes, Volume 18, Issue 9, September 2026.
This cross‐sectional study conducted in the United Arab Emirates investigated Vitamin D status in 102 pediatric patients (ages 3–18) with Type 1 Diabetes Mellitus in the United Arab Emirates, revealing a high prevalence of Vitamin D insufficiency that frequently presents alongside normal parathyroid hormone levels.
Mariam K. Ibrahim, Sara Khan, Karim Siam, Shiefa Sequeria, Rubina Lone   +4 more
wiley   +1 more source

Downregulating CHI3L2 via the STAT3 Pathway: The Mechanism of Calcitriol in Suppressing Psoriatic Inflammation and Keratinocyte Hyperproliferation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Psoriasis is a chronic inflammatory skin disorder driven by immune dysregulation and keratinocyte hyperproliferation. Calcitriol, the active form of vitamin D, shows therapeutic potential, but its molecular mechanisms remain incompletely understood. CHI3L2 (chitinase‐3‐like protein 2) is a member of the chitinase‐like protein family implicated
Qingqing He, Junlin Liu
wiley   +1 more source

ENLIGHTENme: Translating the Benefits of Self‐Administered Daytime Light Supplementation to Older Adults in the Real World

Journal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT Controlled studies have demonstrated that light supplementation benefits circadian entrainment, sleep and mood. Translating these findings into effective, real‐world usage of light supplementation is, however, challenging because naturalistic and supplemental light exposure are shaped by personal habits and environmental light conditions ...
Débora B. Constantino, Flavia Baccari, Leonardo Caporali, Valerio Carelli, Giulia Amore, Marijke Gordijn, Toomas Haller, Chiara La Morgia, Anne Landvreugd, Marina Marinelli, David McDaid, Monika Nõmm, Francesco Nonino, Martina Romagnoli, Martino Schettino, Corrado Zenesini, Meike Bartels, Debra J. Skene, Daan R. van der Veen   +18 more
wiley   +1 more source

Diurnal Variation and Impairment of Postprandial Glucose‐Insulin Responses and Lipid Rhythms in Simulated Shift Work

Nutrition Bulletin, Volume 51, Issue 3, Page 353-365, September 2026.
ABSTRACT Shift work is associated with insulin resistance, dyslipidaemia and metabolic syndrome, but how consecutive meals at the same clock times differentially shape postprandial metabolism in day‐ and night‐shifts remains unclear. This study used a unique simulated shift work intervention with four consecutive meals and high‐resolution sampling to ...
Ameena M. Khan Sullivan, Cheryl M. Isherwood, Hana Hassanin, Debra J. Skene, Daan R. van der Veen   +4 more
wiley   +1 more source

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The VDR FokI (rs2228570) polymorphism is involved in Parkinson's disease

Journal of the Neurological Sciences, 2021
Elisabetta Bolognesi, Mario Clerici, Andrea Sturchio   +2 more
exaly