Results 171 to 180 of about 68,034 (298)

Exploring the Pathogen-Carrying Role of Ixodes Ticks in Vector-Borne Infections [PDF]

Jiří Černý, Geoffrey E. Lynn, Johana Hrnková, Maryna Golovchenko, Nataliia Rudenko, Libor Grubhoffer   +5 more
openalex   +1 more source

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

Advanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv, Peng Chen, Xiaobin Dai, Hu Xu, Ziheng Li, Zelin Shan, Jinqian Li, Fenglin Guo, Yuanfang Chen, Jiayi Li, Yiqian Huang, Guizhi Dong, Yifan Jiang, Liang Chen, Xuanyu Nan, Hanjun Zhao, Kang Zhang, Shilong Fan, Yuanchen Dong, Dongsheng Liu, Xinquan Wang, Deli Huang, Xiaojing Pan, Chunying Chen, Zhihua Liu, Li‐Tang Yan, Qi Zhang, Linqi Zhang, Yuliang Zhao, Yuhe Renee Yang   +29 more
wiley   +1 more source

Mixed Infections, Cryptic Diversity, and Vector-Borne Pathogens: Evidence from Polygenis Fleas and Bartonella Species

, 2007
Patrick Abbot, Alena E. Aviles, Lauren Eller, Lance A. Durden   +3 more
openalex   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

The importance of climatic and ecological factors for vector-borne infections: Culex pipiens and West Nile virus [PDF]

, 2017
Giovanni Marini
openalex  

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Role of immune cell subsets in the establishment of vector‐borne infections [PDF]

, 2012
Wolfgang W. Leitner, Adriana Costero‐Saint Denis, Tonu Wali   +2 more
openalex   +1 more source

Analysis of Multiple Infection in Ixodic Ticks <i>Dermacentor reticulatus</i> in a Combined Natural Focus of Vector-Borne Infections in the Tomsk Region

, 2023
О. В. Воронкова, V. N. Romanenko, A. V. Simakova, И. Е. Есимова, D. A. Dyakov, E. A. Motlokhova, Н. А. Чернышов, D. M. Yamaletdinova   +7 more
openalex   +2 more sources

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Human infections with neglected vector-borne pathogens in China: A systematic review

, 2022
Yan-Qun Sun, Tao Wang, Yuanyuan Zhang, Tian-Le Che, Fanfei Meng, Ai-Ying Teng, Meichen Liu, Tingting Li, Bao‐Gui Jiang, Qiang Xu, Chen‐Long Lv, Jinjin Chen, Nan Zhou, Simon I Hay, Li‐Qun Fang, Wei Liu   +15 more
openalex   +1 more source