Results 151 to 160 of about 1,466,396 (268)

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Nationwide seroprevalence of canine vector-borne pathogens in dogs in Spain. [PDF]

Parasit Vectors
Montoya-Matute A, Checa R, Gómez-Velasco C, Gálvez R, Mendoza I, Sarquis J, Barrera JP, Estévez-Sánchez E, García-Rupérez D, Miró G.   +9 more
europepmc   +1 more source

Targeted‐Penetrating Biomimetic Hybrid Transfersomes for Enhanced Transdermal Gene Transfection in Hypertrophic Scar Therapy

Advanced Science, EarlyView.
Hypertrophic scar fibroblasts membrane‐hybridized cationic transfersomes enable efficient loading and transdermal delivery of TGF‐β1 siRNA through multiple skin penetration pathways. The biomimetic platform enhances homotypic targeting, transfection, and immune evasion, suppresses TGF‐β1‐driven fibrotic signaling, and reduces extracellular matrix ...
Hui Xing, Ziyi Zhao, Yuhui Yang, Yichen Lin, Yinglin Xuan, Ziyang Wang, Kai Lv, Xiaoxu Zhu, Zhi Zhang, Dong Ma   +9 more
wiley   +1 more source

Molecular Detection and Phylogenetic Analysis of Vector-Borne Pathogens from <i>Melophagus ovinus</i> in Qinghai, China. [PDF]

Vet Sci
Zuo M, Zhu P, Yang X, Zhai S, Yang P, Zhou Y, Tan L, Yao J.   +7 more
europepmc   +1 more source

A Multi‐Targeting Chimeric Antigen Receptor‐T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
A dual‐transmembrane Bicephali CAR‐T platform simultaneously targets CD276 and NKG2D ligands to address antigen heterogeneity in non‐small cell lung cancer. By improving immune synapse formation, mitochondrial fitness, antioxidant capacity, and stem‐like persistence, this design enhances durable tumor control and provides a versatile strategy to ...
Lina Wang, Yanlei Zhang, Shuixiu Peng, Chenchen Hou, Huaqi Guo, Tianyu Zhou, Alex H. Chang, Lifeng Yan, Weining Xiong   +8 more
wiley   +1 more source

Inhabiting the host: ectoparasites and Vector-Borne pathogens in Phyllostomidae bats within urban forest fragments. [PDF]

Vet Res Commun
Colácio N, Silva YC, Oliveira LBS, Andrade PGS, Alcântara LP, Alves LGM, Vieira LMC, Campos BH, Diório GF, Gomes-Almeida BK, Carvalho MPN, Braga ÉM, Silveira JAG.   +12 more
europepmc   +1 more source

Spatial and risk factor analyses of vector-borne pathogens among shelter dogs in the Eastern United States. [PDF]

Parasit Vectors, 2023
Hazelrig CM, Gettings JR, Cleveland CA, Varela-Stokes A, Majewska AA, Hubbard K, Burton KW, Yabsley MJ.   +7 more
europepmc   +1 more source

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment

Advanced Science, EarlyView.
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Yidan Zhou, Zhuo Chang, Xianjun Wu, Sijie Wang, Yuzhi Zhang, Hao Zhang, Haoyu Xu, Ruining Peng, Zhe Wang, Huiyun Xu, Yu Liu, Guangkui Xu, Nu Zhang, Hui Yang   +13 more
wiley   +1 more source

Vector-borne pathogen surveillance in a metagenomic world

PLOS Neglected Tropical Diseases
Koray Ergunay, Brian P. Bourke, Nicole Achee, Le Jiang, John Grieco, Yvonne-Marie Linton   +5 more
openaire   +5 more sources

Early-life exposure to vector-borne pathogens in moose calves from Finland: molecular and phylogenetic evidence. [PDF]

BMC Vet Res
Filip-Hutsch K, Oksanen A, Heikkinen P, Asman M, Świsłocka-Cutter M, Młocicki D, Czopowicz M, Anusz K, Isomursu M, Werszko J.   +9 more
europepmc   +1 more source