Results 171 to 180 of about 1,466,396 (268)

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

Animal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao, Haibo Tang, Liang Liang, Jing Leng, Weijian Huang   +4 more
wiley   +1 more source

Vector-borne pathogens of zoonotic concern in dogs from a Quilombola community in northeastern Brazil. [PDF]

Parasitol Res, 2022
de Macedo LO, Bezerra-Santos MA, Filho CRCU, da Silva Sales KG, de Sousa-Paula LC, da Silva LG, Dantas-Torres F, do Nascimento Ramos RA, Otranto D.   +8 more
europepmc   +1 more source

Breed-specific immune regulation under endemic exposure to Leishmania infantum and other vector-borne pathogens in a native Mediterranean canine population. [PDF]

Parasit Vectors
Martínez-Sáez L, Marín-García PJ, Cocco R, Liotta L, Llobat L.   +4 more
europepmc   +1 more source

Human infections with neglected vector-borne pathogens in China: A systematic review. [PDF]

Lancet Reg Health West Pac, 2022
Sun YQ, Wang T, Zhang YY, Che TL, Meng FF, Teng AY, Liu MC, Li TT, Jiang BG, Xu Q, Lv CL, Chen JJ, Zhou N, Hay SI, Fang LQ, Liu W.   +15 more
europepmc   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Role of invasive carnivores (Procyon lotor and Nyctereutes procyonoides) in epidemiology of vector-borne pathogens: molecular survey from the Czech Republic. [PDF]

Parasit Vectors, 2023
Daněk O, Lesiczka PM, Hammerbauerova I, Volfova K, Juránková J, Frgelecová L, Modrý D, Hrazdilova K.   +7 more
europepmc   +1 more source

Editorial: Skin - confluence of vertebrate host defences, arthropod vectors, and vector-borne pathogens. [PDF]

Front Immunol
Narasimhan S, Kazimirova M, Wikel S.
europepmc   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Molecular analysis of vector-borne pathogens in red foxes (<i>Vulpes vulpes</i>) from Saxony-Anhalt (Germany). [PDF]

Int J Parasitol Parasites Wildl
Lindhorst ZTL, Frangl MT, Eigner B, Shahi Barogh B, Duscher GG, Schliephake A, Gaede W, Fuehrer HP, Heddergott M.   +8 more
europepmc   +1 more source