Results 131 to 140 of about 3,417,786 (378)
A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development
The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches.
Arinze Okoli+3 more
doaj +1 more source
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Co-occurrence Vectors from Corpora vs. Distance Vectors from Dictionaries [PDF]
A comparison was made of vectors derived by using ordinary co-occurrence statistics from large text corpora and of vectors derived by measuring the inter-word distances in dictionary definitions. The precision of word sense disambiguation by using co-occurrence vectors from the 1987 Wall Street Journal (20M total words) was higher than that by using ...
arxiv
Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
Flat Vector Bundles over Parallelizable Manifolds [PDF]
We study flat vector bundles over complex parallelizable manifolds.
arxiv
The Integral Representation of Weakly Almost-Periodic Transformations in Reflexive Vector Spaces [PDF]
E. R. Lorch
openalex +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao+4 more
wiley +1 more source