Results 61 to 70 of about 2,671,655 (254)

INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

Molecular Therapy: Methods & Clinical Development, 2017
Integration of new DNA into cellular genomes mediates replication of retroviruses and transposons; integration reactions have also been adapted for use in human gene therapy.
Eric Sherman, Christopher Nobles, Charles C. Berry, Emmanuelle Six, Yinghua Wu, Anatoly Dryga, Nirav Malani, Frances Male, Shantan Reddy, Aubrey Bailey, Kyle Bittinger, John K. Everett, Laure Caccavelli, Mary J. Drake, Paul Bates, Salima Hacein-Bey-Abina, Marina Cavazzana, Frederic D. Bushman   +17 more
doaj   +1 more source

Diversity and potential distribution of culicids of medical importance of the Yucatan Peninsula, Mexico

Salud Pública de México, 2020
Objective. To determine the species distribution, abun­dance, and diversity of culicids in the Yucatan Peninsula (YP); their potential distribution, using ecological niche modeling (ENM), and the risk of contact with urban and rural popula­tions ...
J Guillermo Bond, David A Moo-Llanes, Aldo I Ortega-Morales, Carlos F Marina, Mauricio Casas-Martínez, Rogelio Danis-Lozano   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A viral movement protein mediates host volatile biosynthesis to co-attract vectors and non-vectors and enhances viral infection

Frontiers in Plant Science
The literature shows that vector-transmitted plant viruses mediate host volatile biosynthesis to attract vectors and repel non-vectors, benefiting plant-infecting viruses and enhancing their spread.
Shijun Li, Xiangwen Luo, Xiangwen Luo, Xiangwen Luo, Yu Zhang, Yu Zhang, Zhanhong Zhang, Zhanhong Zhang, Zhanhong Zhang, Xiao Yang, Xiao Yang, Xuguo Zhou, Xin Wang, Xian OuYang, Xian OuYang, Xiaoxin Qu, Deyong Zhang, Deyong Zhang, Deyong Zhang, Deyong Zhang, Songbai Zhang, Songbai Zhang, Songbai Zhang, Songbai Zhang, Yong Liu, Yong Liu, Yong Liu, Yong Liu   +27 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Identification of Novel Zoonotic Activity of Bartonella spp., France

Emerging Infectious Diseases, 2016
Certain Bartonella species are known to cause afebrile bacteremia in humans and other mammals, including B. quintana, the agent of trench fever, and B. henselae, the agent of cat scratch disease.
Muriel Vayssier-Taussat, Sara Moutailler, Françoise Féménia, Philippe Raymond, Olivier Croce, Bernard La Scola, Pierre-Edouard Fournier, Didier Raoult   +7 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Vector Spring 2018

, 2018
Vector is the student engineering magazine on campus. Published by the Student Engineering Council, Vector is completely written, managed, and designed by students for students.
University of Texas at Austin
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Evaluation of seed dressing insecticides for the control of maize lethal necrosis vectors

Cogent Food & Agriculture
Most of the overwhelming plant diseases caused by viruses including maize lethal necrosis (MLN) are attributed to viruses transmitted by vectors. The transmission of MLN from plant to plant by vectors provides the main means of spread in the field and ...
Bayissa Regassa, Adane Abraham, Chemeda Fininsa, Yitbarek Wolde-Hawariat, Dagne Wegary   +4 more
doaj   +1 more source