Results 81 to 90 of about 2,392,273 (315)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Evaluation of seed dressing insecticides for the control of maize lethal necrosis vectors

open access: yesCogent Food & Agriculture
Most of the overwhelming plant diseases caused by viruses including maize lethal necrosis (MLN) are attributed to viruses transmitted by vectors. The transmission of MLN from plant to plant by vectors provides the main means of spread in the field and ...
Bayissa Regassa   +4 more
doaj   +1 more source

Vectorial role of some dermanyssoid mites (Acari, Mesostigmata, Dermanyssoidea)

open access: yesParasite, 2005
Among transmissible diseases, vectorial diseases represent a major problem for public health. In the group of acarina, while ticks are the most commonly implicated vectors, other arthropods and notably Dermanyssoidea are also involved in the transmission
Valiente Moro C., Chauve C., Zenner L.
doaj   +1 more source

Curl-conforming hierarchical vector bases for triangles and tetrahedra [PDF]

open access: yes, 2011
A new family of hierarchical vector bases is proposed for triangles and tetrahedra. These functions span the curl-conforming reduced-gradient spaces of Nédélec.
Peterson A. F.   +9 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Transmission Efficiency, Preference and Behavior of Bemisia tabaci MEAM1 and MED under the Influence of Tomato Chlorosis Virus

open access: yesFrontiers in Plant Science, 2018
Tomato chlorosis virus (ToCV, genus Crinivirus, family Closteroviridae) is an economically important virus in more than 20 countries. In China, ToCV was first detected in 2013 and has already spread throughout the country.
Xiaobin Shi   +8 more
doaj   +1 more source

Vector Surveillance Reports: Northeast Region Program Directory

open access: yes, 2019
The Northeast Regional Center for Excellence in Vector-Borne Diseases is supported through Cooperative Agreement Number 1U01CK000509-01 between the Centers for Disease Control and Prevention (CDC) and Cornell UniversityThis document contains a directory ...
Northeast Regional Center for Excellence in Vector-Borne Diseases
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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