Results 91 to 100 of about 223,733 (327)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Internal functionals and bundle duals
International Journal of Mathematics and Mathematical Sciences, 1984 If π:E→X is a bundle of Banach spaces, X compact Hausdorff, a fibered space π*:E*→X can be constructed whose stalks are the duals of the stalks of the given bundle and whose sections can be identified with the functionals studied by Seda in [1] and [2]
Joseph W. Kitchen, David A. Robbins
doaj +1 more source
Heterotic line bundle models on elliptically fibered Calabi-Yau three-folds
Journal of High Energy Physics, 2018 We analyze heterotic line bundle models on elliptically fibered Calabi-Yau three-folds over weak Fano bases. In order to facilitate Wilson line breaking to the standard model group, we focus on elliptically fibered three-folds with a second section and a
Andreas P. Braun +2 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The Lie Algebra of Smooth Sections of a T-bundle
International Journal of Industrial Engineering and Production Research, 2006 In this article, we generalize the concept of the Lie algebra of vector fields to the set of smooth sections of a T-bundle which is by definition a canonical generalization of the concept of a tangent bundle.
M. Nadjafikhah, H. R. Salimi Moghaddam
doaj
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Journal of High Energy PhysicsThe group of vertical diffeomorphisms of a principal bundle forms the action Lie groupoid associated to the bundle. The former is generated by the group of maps with value in the structure group, which is also the group of bisections of the groupoid. The
J. François
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Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Stable geometric dimension of vector bundles over even-dimensional real projective spaces [PDF]
, 2005 Martin Bendersky +2 more
openalex +1 more source