Results 91 to 100 of about 223,260 (263)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Internal functionals and bundle duals

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1984
If π:E→X is a bundle of Banach spaces, X compact Hausdorff, a fibered space π*:E*→X can be constructed whose stalks are the duals of the stalks of the given bundle and whose sections can be identified with the “functionals” studied by Seda in [1] and [2]
Joseph W. Kitchen, David A. Robbins
doaj   +1 more source

Heterotic line bundle models on elliptically fibered Calabi-Yau three-folds

open access: yesJournal of High Energy Physics, 2018
We analyze heterotic line bundle models on elliptically fibered Calabi-Yau three-folds over weak Fano bases. In order to facilitate Wilson line breaking to the standard model group, we focus on elliptically fibered three-folds with a second section and a
Andreas P. Braun   +2 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

The Lie Algebra of Smooth Sections of a T-bundle

open access: yesInternational Journal of Industrial Engineering and Production Research, 2006
In this article, we generalize the concept of the Lie algebra of vector fields to the set of smooth sections of a T-bundle which is by definition a canonical generalization of the concept of a tangent bundle.
M. Nadjafikhah, H. R. Salimi Moghaddam
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Note on the group of vertical diffeomorphisms of a principal bundle & its relation to the Frölicher-Nijenhuis bracket

open access: yesJournal of High Energy Physics
The group of vertical diffeomorphisms of a principal bundle forms the action Lie groupoid associated to the bundle. The former is generated by the group of maps with value in the structure group, which is also the group of bisections of the groupoid. The
J. François
doaj   +1 more source

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