Results 81 to 90 of about 223,733 (327)
On a Lie Algebraic Characterization of Vector Bundles
Symmetry, Integrability and Geometry: Methods and Applications, 2012 We prove that a vector bundle π: E→M is characterized by the Lie algebra generated by all differential operators on E which are eigenvectors of the Lie derivative in the direction of the Euler vector field.
Pierre B.A. Lecomte +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A Geometric characterization of Finsler manifolds of constant curvature K=1
International Journal of Mathematics and Mathematical Sciences, 2000 We prove that a Finsler manifold 𝔽m is of constant curvature K=1 if and only if the unit horizontal Liouville vector field is a Killing vector field on the indicatrix bundle IM of 𝔽m.
A. Bejancu, H. R. Farran
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Affine analogues of the Sasaki-Shchepetilov connection
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2016 For two-dimensional manifold M with locally symmetric connection ∇ and with ∇-parallel volume element vol one can construct a flat connection on the vector bundle TM⊕E, where E is a trivial bundle.
Maria Robaszewska
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Generalized Fourier-Mukai Transforms
, 1996 The paper sets out a generalized framework for Fourier-Mukai transforms and illustrates their use via vector bundle transforms. A Fourier-Mukai transform is, roughly, an isomorphism of derived categories of (sheaves) on smooth varieties X and Y.
Maciocia, Antony
core +1 more source