Results 81 to 90 of about 217,155 (332)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Solutions of the Strominger System via Stable Bundles on Calabi-Yau Threefolds

, 2012
We prove that a given Calabi-Yau threefold with a stable holomorphic vector bundle can be perturbed to a solution of the Strominger system provided that the second Chern class of the vector bundle is equal to the second Chern class of the tangent bundle.
A. Sen, A. Strominger, B. Andreas, B. Andreas, B. Andreas, Björn Andreas, C.-D. Hill, C.-M. Hull, D. Gilbarg, D. Huybrechts, E. Witten, E. Witten, E. Witten, J. Distler, J. Fu, J. Li, J.-X. Fu, J.-X. Fu, K. Uhlenbeck, M. C. Brambilla, M. Fernández, M. Lübke, M. Maruyama, M. Reid, M.R. Douglas, Mario Garcia-Fernandez, P. Candelas, R. Friedman, R. Friedman, R. Friedman, S. Ivanov, S. Ivanov, S.K. Donaldson, T. Aubin, X. Wu   +34 more
core   +1 more source

Uniformity of Vector Bundles of Finite Rank on Complete Intersections of Finite Codimension in a Linear ind-Grassmannian

Моделирование и анализ информационных систем, 2015
A linear projective ind-variety X is called 1-connected if any two points on it can be connected by a chain of lines l1, l2, ..., lk in X, such that li intersects li+1.
S. M. Yermakova
doaj   +1 more source

Brill-Noether-general limit root bundles: absence of vector-like exotics in F-theory Standard Models

Journal of High Energy Physics, 2022
Root bundles appear prominently in studies of vector-like spectra of 4d F-theory compactifications. Of particular importance to phenomenology are the Quadrillion F-theory Standard Models (F-theory QSMs).
Martin Bies, Mirjam Cvetič, Ron Donagi, Marielle Ong   +3 more
doaj   +1 more source

A Cohomological Class of Vector Bundles [PDF]

Proceedings of the American Mathematical Society, 1994
The goal of this paper is to give a cohomological characterization of F n , t {F_{n,t}} , where F n , t := Ker ⁡ ( (
openaire   +3 more sources

Stability of complex vector bundles [PDF]

Journal of Differential Geometry, 1996
Stability of complex vector ...
Gang Tian, Paolo De Bartolomeis, Paolo De Bartolomeis   +2 more
openaire   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Polystable bundles and representations of their automorphisms

Complex Manifolds, 2022
Using a quasi-linear version of Hodge theory, holomorphic vector bundles in a neighbourhood of a given polystable bundle on a compact Kähler manifold are shown to be (poly)stable if and only if their corresponding classes are (poly)stable in the sense of
Buchdahl Nicholas, Schumacher Georg
doaj   +1 more source

Monads and vector bundles on quadrics [PDF]

advg, 2008
Abstract We improve Ottaviani's splitting criterion for vector bundles on a quadric hypersurface and obtain the equivalent of the result by Rao, Mohan Kumar and Peterson. Then we give the classification of rank 2 bundles without “inner” cohomology on 𝒬 n (n > 3).
openaire   +4 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source