Results 91 to 100 of about 162,218 (329)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Hunting Vector Bundles on $\mathbb{P}^1 \times \mathbb{P}^1$ [PDF]
, 2017 Pablo Solis
openalex +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Connections on trivial vector bundles over projective schemes
Comptes Rendus. MathématiqueOver a smooth and proper complex scheme, the differential Galois group of an integrable connection may be obtained as the closure of the transcendental monodromy representation.
Biswas, Indranil +2 more
doaj +1 more source
Newton-Okounkov bodies on projective bundles over curves
, 2017 In this article, we study Newton-Okounkov bodies on projective vector bundles over curves. Inspired by Wolfe's estimates used to compute the volume function on these varieties, we compute all Newton-Okounkov bodies with respect to linear flags. Moreover,
Montero, Pedro
core
Infinite dimensional families of Calabi-Yau threefolds and moduli of vector bundles [PDF]
, 2019 Edoardo Ballico +2 more
openalex +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
A note about scalar curvature on the total space of a vector bundle [PDF]
, 2019 Jialong Deng
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