Results 131 to 140 of about 2,245,201 (365)

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

open access: yesAdvanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye   +20 more
wiley   +1 more source

Development of replication-competent adenovirus based vaccine vectors [PDF]

open access: yesRetrovirology, 2012
Background Replication-incompetent adenovirus vectors have shown promise as vaccine candidates. We are developing replication-competent adenovirus vectors to increase antigen expression and duration and to facilitate mucosal routes of vaccine delivery.
Dan H. Barouch   +2 more
openaire   +3 more sources

Randomized Reference Classifier with Gaussian Distribution and Soft Confusion Matrix Applied to the Improving Weak Classifiers

open access: yes, 2019
In this paper, an issue of building the RRC model using probability distributions other than beta distribution is addressed. More precisely, in this paper, we propose to build the RRR model using the truncated normal distribution.
B. Bergmann   +23 more
core   +1 more source

Influences on classification accuracy of exam sets: an example from vocational education and training [PDF]

open access: yes, 2012
Classification accuracy of single exams is well studied in the educational measurement literature. However, when making important decisions, such as certification decisions, one usually uses several exams: an exam set.
Eggen, T.J.H.M., Hubregtse, M.
core   +3 more sources

Mixed Ionic and Electronic Charge Transport in Conductive Protein Fibers Revealed with DC Electrical Measurements

open access: yesAdvanced Materials, EarlyView.
M13 bacteriophage films deposited on micro interdigitated electrodes behave as a Randles simplified equivalent circuit under direct current. We derive contact and film resistance as well as capacitance of films of M13 phages, aromatic curli fibers or pilA‐containing nanowires.
Daniel Modafferi   +6 more
wiley   +1 more source

Mosquitoes as Arbovirus Vectors: From Species Identification to Vector Competence

open access: yes, 2018
Mosquitoes and other arthropods transmit a large number of medically important pathogens, in particular viruses. These arthropod-borne viruses (arboviruses) include a wide variety of RNA viruses belonging to the Flaviviridae family (West Nile virus (WNV), Usutu virus (USUV), Dengue virus (DENV), Japanese encephalitis virus (JEV), Zika virus (ZIKV ...
Stefanie C. Becker, Claudia Schulz
openaire   +2 more sources

Replication-competent herpes simplex vectors: design and applications [PDF]

open access: yesGene Therapy, 2005
Replication-competent vectors are derived from attenuated viruses whose genes, that are nonessential for replication in cultured cells in vitro, are either mutated or deleted. The removal of one or more nonessential genes may reduce pathogenicity without requiring a cell line to complement growth.
ARGNANI, Rafaela   +3 more
openaire   +3 more sources

The Intersection between Chickering’s Theory and Generation Z Student of Color Activism [PDF]

open access: yes, 2019
Student activism is an ever-developing trend on college campuses. The current generation, Generation Z, started college in 2013. Analyzing literature on student development and how it intersects with the student activist identity reveals what ...
Tanaid, Kayla L., Wright, Kevin L.
core   +1 more source

Genetic Surfaceome E. coli Reprogramming Enables Selective Water Oxidation

open access: yesAdvanced Materials, EarlyView.
A novel enzymatic material based on bilirubin oxidase (BOD) surface‐expressed on E. coli for effective electrocatalysis is reported. With this material, highly efficient and selective water oxidation is achieved, a critical half reaction for synthetic photosynthesis. Abstract Programming catalytic behavior at the microbial genome level is a frontier in
Graziela C. Sedenho   +6 more
wiley   +1 more source

Vector competence of Aedes vittatus (Bigot) mosquitoes from India for Japanese encephalitis, West Nile, Chandipura and Chittoor viruses

open access: yesJournal of Vector Borne Diseases, 2020
Background & objectives: Aedes vittatus (Bigot), an anthropophilic mosquito, plays an important role in the maintenance and transmission of yellow fever (YF), dengue (DEN), chikungunya (CHIKV) and Zika (ZIK) viruses in Africa.
A B Sudeep   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy