Results 131 to 140 of about 1,527,304 (285)
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics
Advanced Science, EarlyView.A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma +22 more
wiley +1 more source
A Survey on Potential of the Support Vector Machines in Solving Classification and Regression Problems [PDF]
Kernel methods and support vector machines have become the most popular learning from examples paradigms. Several areas of application research make use of SVM approaches as for instance hand written character recognition, text categorization, face ...
Catalina COCIANU +2 more
core
Advanced Science, EarlyView.Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku +4 more
wiley +1 more source
Advanced Science, EarlyView.ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila
Advanced Science, EarlyView.While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li +7 more
wiley +1 more source
Vector competence and filariasis transmission in Mali [PDF]
, 2017 Lymphatic filariasis (LF) is a public health problem in 73 countries and is associated with marked morbidity and disability. It is unique because of its transmission by five main genera of mosquitoes, including Culex, Aedes, Anopheles, Mansonia and Ochlerotatus. In Mali, LF endemicity mapping in 2004 found all eight administrative regions to be endemic
openaire +1 more source
, 2019 Table of Contents: Why Antivaxx has Gone Viral (p. 4) -- Cut and Paste (p. 6) -- Scooter Mayhem (p. 8) -- The Automation Dilemma (p. 10) -- Humanitarian Design (p. 12) -- Inclusivity in Engineering (p. 14) -- Undocumented Students (p.
University of Texas at Austin
core +1 more source
A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Advanced Science, EarlyView.Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
, 2018 Table of Contents: The Digital Dreamland (p. 4) -- The Earliest Online Communities (p. 6) -- Nostalgic Thoughts (p. 9) -- The Evolution of Social Media (p. 10) -- The Digital Divide (p. 12) -- The Deep Web (p. 14) -- The Future of Fitness (p.
University of Texas at Austin
core +1 more source