Results 181 to 190 of about 2,190,858 (340)

Studies on vector competence of Culex (Cx) tarsalis Coq from an epidemic/epizootic area in Iowa for an enzootic strain of western equine encephalomyelitis (WEE-7738) virus and vertical transmission of the WEE virus in Aedes (Ae) trivittatus (Coq)

, 1998
Joon‐Hak Lee
openalex   +2 more sources

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Vector competence of Australian Aedes aegypti and Aedes albopictus for an epidemic strain of Zika virus

, 2019
Leon E. Hugo, Liesel Stassen, Jessica La, Edward Gosden, O’mezie Ekwudu, Clay Winterford, Elvina Viennet, Helen M. Faddy, Gregor J. Devine, Francesca D. Frentiu   +9 more
openalex   +2 more sources

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

Advanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong, Jun Song, Shihan Li, Lu Jin, Qi He, Baohui Zhang, Yan Cao, Shanyong Yi, Yanfang Yang, Xiang Li, Juan Li, Wei Huang   +11 more
wiley   +1 more source

Microbiome diversity in mosquitoes and sand flies: implications for vector competence. [PDF]

Parasit Vectors
Ragini G, Mani MK, Sharma R, Bharadwaj N, Subramanian M, Nagarajan SA, Rahi M.   +6 more
europepmc   +1 more source

Expanding frontiers of the Chikungunya virus: vector competence, ecology, and surveillance challenges in urban and wild environments

Cíntia da Silva Varzim, Jaqueline Dilly, Aline Otto Pfeifer, Harry Luiz Pilz, José Oliveira, Luciana Dalla Rosa, Onilda Santos da Silva, Carlos Eugênio Silva   +7 more
openalex   +2 more sources

Vector competence of Aedes aegypti, Aedes albopictus , and Culex quinquefasciatus mosquitoes for Mayaro virus [PDF]

, 2019
Thiago Nunes Pereira, Fabiano Duarte Carvalho, Silvana F. de Mendonça, Marcele Neves Rocha, Luciano Andrade Moreira   +4 more
openalex   +1 more source

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

The making of a dangerous vector: factors shaping the vector competence of <i>Aedes</i> mosquitoes. [PDF]

Front Cell Infect Microbiol
Wu Y, Wu J, Wu Q, Cai H, Hu J, Lin Z, Liao R.   +6 more
europepmc   +1 more source