Advanced Science, EarlyView.A genome‐scale model guided the systematic metabolic engineering of Saccharopolyspora spinosa, enabling a 5.5‐fold boost in the green bioinsecticide spinosad to 1.8 g L−1 and establishing an actinomycete framework for complex natural products overproduction.
Shuliu Wang +9 more
wiley +1 more source
Political Budget Cycles: A Review of Recent Developments [PDF]
This paper provides a review of recent developments in the theory and evidence of political budget cycles. Specifically, we discuss three areas where significant progress has been made.
Jakob Svensson, Min Shi
core
Survey of the vectorial competence of ticks in an endemic area of spotted fever group rickettsioses in Fukui Prefecture, Japan [PDF]
, 2008 Fubito Ishiguro +5 more
openalex +1 more source
Vector Competence of Florida Culicoides insignis (Diptera: Ceratopogonidae) for Epizootic Hemorrhagic Disease Virus Serotype-2 [PDF]
, 2021 Bethany L. McGregor +5 more
openalex +1 more source
CRISPR‐DNA Polymerase Assisted Targeted Mutagenesis for Regulable Laboratory Evolution
Advanced Science, EarlyView.This study develops an in vivo targeted mutagenesis system based on CRISPR‐guided bacteriophage T5 or T7 DNA polymerases. This system can enable all possible types of substitution mutations within an expanded mutagenesis window in Escherichia coli and exhibit application potential in different microorganisms, thus accelerating the evolution of ...
Shuaili Chen +8 more
wiley +1 more source
Which doctor? Combining vignettes and item response to measure doctor quality [PDF]
The authors develop a method in which vignettes-a battery of questions for hypothetical cases-are evaluated with item response theory to create a metric for doctor quality. The method allows a simultaneous estimation of quality and validation of the test
Das, Jishnu, Hammer, Jeffrey
core
Vector Competence of Three Australian Mosquitoes,Verrallina carmenti,Verrallina lineata, andMansonia septempunctata(Diptera: Culicidae), for Ross River Virus [PDF]
, 2008 Cameron Webb +3 more
openalex +1 more source
Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence [PDF]
, 2021 Ehud Inbar +10 more
openalex +1 more source
Advanced Science, EarlyView.Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun +13 more
wiley +1 more source
Factors determining vector competence and specificity for transmission of Tomato spotted wilt virus
, 2002 Tatsuya Nagata +4 more
openalex +1 more source