Results 301 to 310 of about 2,190,858 (340)

Vector Competence of Australian Mosquitoes for Chikungunya Virus

Vector-Borne and Zoonotic Diseases, 2010
Chikungunya virus (CHIKV) is a globally emerging arbovirus responsible for unprecedented outbreaks in the western Indian Ocean, the Indian subcontinent and Italy. To assess the receptivity of Australia to CHIKV, we exposed 10 Australian mosquito species to a 2006 strain of CHIKV isolated from a viremic traveler from Mauritius. In susceptibility trials,
Van Den Hurk, AF, Hall-Mendelin, S, Pyke, AT, Smith, GA, Mackenzie, JS   +4 more
openaire   +3 more sources

Generation of Replication-Competent and -Defective HSV Vectors

Cold Spring Harbor Protocols, 2011
INTRODUCTIONEngineering effective vectors has been crucial to the efficient delivery and expression of therapeutic gene products in vivo. Among these, HSV-1 represents an excellent candidate vector for delivery to the peripheral and central nervous systems. The natural biology of HSV-1 includes the establishment of a lifelong latent state in neurons in
William F, Goins, David M, Krisky, James B, Wechuck, Darren, Wolfe, Shaohua, Huang, Joseph C, Glorioso   +5 more
openaire   +2 more sources

Antibody-Mediated Targeting of Replication-Competent Retroviral Vectors

Human Gene Therapy, 2003
Replication-competent murine leukemia virus (MLV) vectors can be engineered to achieve high efficiency gene transfer to solid tumors in vivo and tumor-restricted replication, however their safety can be further enhanced by redirecting tropism of the virus envelope. We have therefore tested the targeting capability and replicative stability of ecotropic
Chien-Kuo, Tai, Christopher R, Logg, Jinha M, Park, W French, Anderson, Michael F, Press, Noriyuki, Kasahara   +5 more
openaire   +2 more sources

Monitoring Lentivirus Vector Stocks for Replication-Competent Viruses

Cold Spring Harbor Protocols, 2018
The potential emergence of replication-competent lentiviruses (RCLs) during vector production and the significant biosafety risk that this represents has led to the development of lentivirus vector production systems to minimize the risk of generating RCLs.
Miguel, Sena-Esteves, Guangping, Gao
openaire   +2 more sources

Vector Competence Assays for RVFV in Mosquitoes

Rift Valley fever virus (RVFV) is the causative agent of Rift Valley fever, a mosquito-borne zoonotic febrile illness that primarily affects ruminants, camels, and humans. It is endemic in sub-Saharan Africa and the Arabian Peninsula, albeit with the potential to spread to and establish in non-endemic countries where mosquito vectors are present ...
Lotty, Birnberg, Núria, Busquets
openaire   +2 more sources

Effect of Vector Density and Competence on Macromolecular Vector Transformation Efficiency

2016
To research the effects of vector quantity and competence on the positive cloning rate, with a known gene sequence but in the absence of DNA template, we artificially designed 26 primers to synthesize a target gene of 835 bp in vitro using overlapping PCR technique.
QIN, Hongni, ZHANG, Lanlan, QIN, Hongni, ZHANG, Lanlan   +3 more
openaire   +1 more source

Vector microbiome: will global climate change affect vector competence and pathogen transmission?

Parasitology Research, 2022
Daniela de Angeli Dutra, P. M. Salloum, R. Poulin   +2 more
semanticscholar   +1 more source

Host plant influences life cycle, reproduction, feeding, and vector competence of Thrips palmi (Thysanoptera: Thripidae), a vector of tospoviruses

Phytoparasitica, 2021
Heena Dhall, Sumit Jangra, Y. Basavaraj, Amalendu Ghosh   +3 more
semanticscholar   +1 more source

Viral vector platforms within the gene therapy landscape

Signal Transduction and Targeted Therapy, 2021
Phillip W L Tai, Guangping Gao
exaly  

Vector competence

Parasitology Today, 1992
openaire   +2 more sources