Results 71 to 80 of about 8,483,852 (303)

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Molecular identification of wild caught phlebotomine sand flies (Diptera, Psychodidae) by mitochondrial DNA barcoding in India

Scientific Reports
Sand flies are medically important insects with diverse distributions and roles in pathogen transmission. Globally, over a thousand species have been documented, with Indian sand fly fauna currently comprising 71 species.
Harish Kumar Shah, P. A. Fathima, Bhavna Gupta, Manju Rahi, Prasanta Saini   +4 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

A multicentric study on understanding the bionomics of Indian malaria vectors across diverse eco-epidemiological settings

Parasites & Vectors
Background India aims to eliminate malaria by 2030; however, a thorough understanding of the current biology and behavior of vector species will facilitate the efforts.
Ajeet Kumar Mohanty, Alex Eapen, Himmat Singh, Kuldeep Singh, Rajendra Kumar Baharia, Vidhan Jain, Debattam Mazumdar, Sachin Sharma, A. N. Shriram, P. T. Vidhya, Amit Sharma, Kannan Thiruvengadam, Manju Rahi   +12 more
doaj   +1 more source

On Resolving Vector Fields

Journal of Algebra, 1997
Let \(V\) be a singular affine irreducible variety over a field \(k\) and \(\mathcal{D}\) an \(\mathcal{O}_{V}\)-module of \(k\)-linear derivations. Suppose that \(I \subset \mathcal{O}_{V}\) is an ideal such that , for the blow-up \(\tilde{V} =BL_{I}(V)\), \(\mathcal{O}_{\tilde{V}}\cdot \mathcal{D}(\mathcal{O}_{\tilde{V}})\) is locally free.
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Age and sex distribution trends of SARS-CoV-2 infections: Insights from three epidemic waves in Puducherry, India

Journal of Infection in Developing Countries
Introduction: This study analyzed the age and sex distribution of COVID-19 patients during the initial three COVID-19 waves in Puducherry, India, from August 2020 to March 2022, to understand the distribution of infection across different demographic ...
Lourduraj John De Britto, Arya Rahul, Dinesh Sundaram, Balakrishnan Vijayakumar, Thirumal Sankari, Muthukumaravel Subramanian, Raja Jeyapal Dinesh, Philip Raj Abraham, Panneer Devaraju, Yasin Nazeer, Ayyanar Elango, Balasubramaniyan Ramalingam, Kulandaisamy Athisaya Mary, Suchi Tyagi, Rituraj Niranjan, Paramasivan Rajaiah, Mayilsamy Muniaraj, Narendran Pradeep Kumar, Irudayaraj Geetha, Ananganallur Nagarajan Shriram, Adinarayanan Srividya, Vijesh Sreedhar Kuttiatt, Ashwani Kumar   +22 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Diversity and spatiotemporal distribution of mosquitoes (Diptera: Culicidae) with emphasis on disease vectors across agroecological areas of Kerala, India

Scientific Reports
Mosquitoes are important vectors of several diseases that significantly impact public health globally. This multi-district mosquito survey revealed the diversity and distribution of mosquito species across varied agroecological areas in Kerala, India ...
L. Mathiarasan, R. Natarajan, A. Aswin, N. A. Johnson Amala Justin, Nivetha Thampi, Manisha Kumari, G. Sri Lakshmi Priya, P. D. Rohini, S. Gopalakrishnan, P. Jambulingam, Alex Eapen   +10 more
doaj   +1 more source

Vector Spring 2017 [PDF]

, 2017
Vector is the student engineering magazine on campus. Published by the Student Engineering Council, Vector is completely written, managed, and designed by students for students.
University of Texas at Austin
core   +1 more source