Results 211 to 220 of about 946,872 (311)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Cloning, heterologous expression, and expression analysis of SinSyn7 gene from Sinomenium acutum. [PDF]

PLoS One
Chen J, Chen X, Zhang L, Huang S, Chen X, Huang X, Yang H.   +6 more
europepmc   +1 more source

A Sustainable Biotechnology Approach for Mineral Separation

Advanced Functional Materials, EarlyView.
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang, Yun Liu, Shankar Raj Devkota, Yue Hui, Ruilin Zhao, Yang Li, David A. Weitz, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Effective polyclonal antibodies against the virulence-associated protein D (VapD) of Helicobacter pylori, obtained from recombinant VapD. [PDF]

PLoS One
Flores-Alanis A, Delgado G, Santiago-Olivares C, Luna-Pineda VM, Cruz-Rangel A, Guerrero-Mejía D, Escobar-Sánchez ML, Torres-Ramírez N, Morales-Espinosa R.   +8 more
europepmc   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Efficient, cell-type-specific production of flavonols by multiplexed CRISPR activation of a suite of metabolic enzymes. [PDF]

Nat Commun
Houbaert A, Denervaud Tendon V, Hoermayer L, Morffy N, Strader LC, Geldner N.   +5 more
europepmc   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Correction for Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. [PDF]

Mol Biol Cell
europepmc   +1 more source

Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection

Advanced Functional Materials, EarlyView.
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung, Yujin Ahn, Joo Hun Lee, Seungju Yang, Seung Cheol Lee, Hyunjoon Kong, Hyun Jung Chung   +6 more
wiley   +1 more source

New insights into the life cycle, host cell tropism, and infection amplification of <i>Leishmania</i> spp. [PDF]

Infect Immun
Silva-Moreira AL, Serravite AM, Rios-Barros LV, de Menezes JPB, Horta MF, Castro-Gomes T.   +5 more
europepmc   +1 more source