Results 21 to 30 of about 1,003,393 (301)

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source

Genome-wide identification and expression profiling of odorant receptor genes in the malaria vector Anopheles sinensis

Parasites & Vectors, 2022
Background The olfactory system plays a crucial role in regulating insect behaviors. The detection of odorants is mainly mediated by various odorant receptors (ORs) that are expressed in the dendrites of olfactory neurons of chemosensilla.
Zhengbo He, Zhengrong Yu, Xingfei He, Youjin Hao, Liang Qiao, Shihui Luo, Jingjing Zhang, Bin Chen   +7 more
doaj   +1 more source

Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]

, 2015
[No abstract ...
A Berry, A Koukounari, AJ Norton, AR Laird, B Schelkle, BL Webster, BL Webster, BL Webster, BR Grant, C Astrom, C Gyles, CA Machado, CD Criscione, CM Brasier, CM Lively, CM Lively, CS Clarkson, CS Wondji, D Menge, D Rollinson, D Weetman, DB Dunams-Morel, DE Neafsey, Deborah F. Smith, DR Brooks, DR Dittrich-Reed, E Inbar, E Mancini, E Redman, E Strauch, EH Stukenbrock, EJ Baack, GL Nichols, Glenn F Rall, H Krehenwinkel, H Ochman, H Ochman, HD Mawejje, HJ Müller, HV Pates, I Goodhead, J Boissier, J Davies, J Hawks, J Mallet, J Mavarez, JA Coyne, JA Patz, JC Semenza, JM Kelly, Joanne P. Webster, JP Webster, JP Webster, JT Detwiler, Kayla C. King, KD Lafferty, LA Messenger, LA Messenger, LAT Tchuente, LC Norris, LH Rieseberg, LH Rieseberg, M Arnold, M Lynch, M Schumer, M Worobey, MA Miles, MA Nowak, MB Rogers, MB Rogers, MC Fontaine, ME Grigg, MF Dybdahl, MG Taylor, Michael A. Brockhurst, MJ Gibbs, ML Arnold, ML Arnold, ML Steinauer, MW Gaunt, NH Barton, NR Sturm, NS Akopyants, O Seehausen, P Martens, P Volf, P Volf, PW Hedrick, R Abbott, RA Farrer, RB Stelkens, RB Stelkens, RDH Barrett, Rike B. Stelkens, RS Ramiro, S Edmands, S Hales, S Manguin, S Moore, T Dobzhansky, T Huyse, T Huyse, TH Le, U Chaudhry, W Alves, W Choochote, W Li, Y Lee, Y Song   +108 more
core   +2 more sources

Physical constraints on accuracy and persistence during breast cancer cell chemotaxis [PDF]

, 2019
Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis.
Han, Bumsoo, Moon, Hye-ran, Mugler, Andrew, Saha, Soutick, Varennes, Julien   +4 more
core   +4 more sources

Complex genome evolution in Anopheles coluzzii associated with increased insecticide usage in Mali. [PDF]

, 2015
In certain cases, a species may have access to important genetic variation present in a related species via adaptive introgression. These novel alleles may interact with their new genetic background, resulting in unexpected phenotypes.
Brisco, Katherine, Collier, Travis C, Cornel, Anthony J, Fofana, Abdrahamane, Lanzaro, Gregory C, Lee, Yoosook, Main, Bradley J, Norris, Laura C   +7 more
core   +1 more source

A new species in the major malaria vector complex sheds light on reticulated species evolution [PDF]

, 2019
Complexes of closely related species provide key insights into the rapid and independent evolution of adaptive traits. Here, we described and studied Anopheles fontenillei sp.n., a new species in the Anopheles gambiae complex that we recently discovered ...
Akone-Ella O., Ayala D., Barron M. G., Costantini C., Gonzalez J., Kengne P., Ngangue M. F., Paupy C., Pombi M., Rahola N., Simard F., Wilson-Bahun T. A.   +11 more
core   +1 more source

A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase [PDF]

, 2013
Biotin-dependent enzymes catalyze carboxyl transfer reactions by efficiently coordinating multiple reactions between spatially distinct active sites. Pyruvate carboxylase (PC), a multifunctional biotin-dependent enzyme, catalyzes the bicarbonate- and ...
Lietzan, Adam D, Maurice, Martin St.
core   +2 more sources

Efficacy and safety of dihydroartemisinin–piperaquine for the treatment of uncomplicated Plasmodium falciparum and Plasmodium vivax malaria in Papua and Sumatra, Indonesia

Malaria Journal, 2022
Background Dihydroartemisinin–piperaquine (DHA–PPQ) has been adopted as first-line therapy for uncomplicated falciparum malaria in Indonesia since 2010.
Puji B. S. Asih, Ismail E. Rozi, Farahana K. Dewayanti, Suradi Wangsamuda, Syarifah Zulfah, Marthen Robaha, Jonny Hutahaean, Nancy D. Anggraeni, Marti Kusumaningsih, Pranti S. Mulyani, Elvieda Sariwati, Herdiana H. Basri, Maria Dorina G. Bustos, Din Syafruddin   +13 more
doaj   +1 more source

Molecular biology on a microfluidic chip [PDF]

, 2006
We have developed microfluidic chips for automating molecular biology processes such as gene ligation and gene transformation from nanolitre sample volumes with parallel architecture. Unlike conventional tube methods with cumbersome pipetting procedures,
Anderson, W. French, Chen, Yan, Hong, Jong Wook, Quake, Stephen R.   +3 more
core   +1 more source

A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. [PDF]

, 2013
The endoplasmic reticulum-associated degradation (ERAD) pathway is responsible for disposing misfolded proteins from the endoplasmic reticulum by inducing their ubiquitination and degradation.
Anania, Veronica, Bustos, Daisy, COSCOY, Laurent, Kirkpatrick, Donald, Lill, Jennie   +4 more
core   +3 more sources