Results 31 to 40 of about 236,579 (156)

Modified Hematopoietic Stem Cell-Derived Dendritic Cell Therapy Retained Tumor-Inhibitory Function and Led to Regression of Primary and Metastatic Pancreatic Tumors in Humanized Mouse Models

Vaccines
Background/Objectives: Dendritic cell (DC)-based immunotherapies offer a promising strategy for cancer treatment but are limited by inefficient activation of cytotoxic T cells and, in turn, the host immune system.
Jose D. Gonzalez, Saleemulla Mahammad, Senay Beraki, Ariel Rodriguez-Frandsen, Neha Sheik, Elango Kathirvel, Francois Binette, David Weinstein, Anahid Jewett, Lu Chen   +9 more
doaj   +1 more source

mRNA Vaccines: Current Applications and Future Directions

MedComm
Messenger RNA (mRNA) vaccines, as a novel class of biotherapeutics, leverage mRNA technology to instruct cells to produce specific antigens, thereby inducing an immune response.
Jianmei Li, Yixin Liu, Jie Dai, Li Yang, Feng Xiong, Jing Xia, Jing Jin, Yangping Wu, Xingchen Peng   +8 more
doaj   +1 more source

Existence of Solutions for Nonconvex and Nonsmooth Vector Optimization Problems

Journal of Inequalities and Applications, 2008
We consider the weakly efficient solution for a class of nonconvex and nonsmooth vector optimization problems in Banach spaces. We show the equivalence between the nonconvex and nonsmooth vector optimization problem and the vector variational-like ...
Nan-Jing Huang, Jong Kyu Kim, Zhi-Bin Liu   +2 more
doaj   +2 more sources

About one discrete analog of Hausdorff semi-continuity of suitable mapping in a vector combinatorial problem with a parametric principle of optimality ("from Slater to lexicographic")

Journal of Numerical Analysis and Approximation Theory, 2006
multicriteria linear combinatorial problem is considered, principle of optimality of which is defined by a partitioning of partial criteria onto groups with Slater preference relation within each group and the lexicographic preference relation ...
Vladimir A. Emelichev, Andrey A. Platonov   +1 more
doaj   +2 more sources

GENERALIZATION ALGORITHM OF PROBLEM SOLUTION FOR VECTOR OPTIMIZATION THROUGH TWO INDEXES AND CHOOSE FLEXIBLE TECHNOLOGY FOR CARS REPAIR

Nauka ta progres transportu, 2010
The mathematical formulation of solution algorithm for a vector optimization problem on two indices with regard to scientific substantiation of a flexible line of car repair is presented in the ...
V. V. Myamlin, A. A. Bosov, S. V. Myamlin   +2 more
doaj  

Connectedness and Path Connectedness of Weak Efficient Solution Sets of Vector Optimization Problems via Nonlinear Scalarization Methods

Mathematics, 2019
The connectedness and path connectedness of the solution sets to vector optimization problems is an important and interesting study in optimization theories and applications.
Xin Xu, Yang Dong Xu
doaj   +1 more source

Classification of corn kernels grades using image analysis and support vector machine

Advances in Mechanical Engineering, 2018
In order to classify the quality of corn kernels in an affordable, convenient, and accurate manner, a method based on image analysis and support vector machine is proposed.
Ang Wu, Juanhua Zhu, Yuli Yang, Xinping Liu, Xiushan Wang, Ling Wang, Hao Zhang, Jing Chen   +7 more
doaj   +1 more source

A fault diagnosis method of rolling bearing

Gong-kuang zidonghua, 2014
For parameter optimization of support vector machine in fault diagnosis method of rolling bearing based on support vector machine, an improved fruit fly optimization algorithm was proposed which took accuracy rate of pattern classification as taste ...
DONG Jianping, YANG Cheng, LU Xiaoli
doaj   +1 more source

Traffic fatalities prediction using support vector machine with hybrid particle swarm optimization

Journal of Algorithms & Computational Technology, 2018
Road traffic safety is essential, therefore in order to predict traffic fatalities effectively and promote the harmonious development of transportation, a traffic fatalities prediction model based on support vector machine is established in this paper ...
Xiaoning Gu, Ting Li, Yonghui Wang, Liu Zhang, Yitian Wang, Jinbao Yao   +5 more
doaj   +1 more source

Target-Cell-Directed Bioengineering Approaches for Gene Therapy of Hemophilia A

Molecular Therapy: Methods & Clinical Development, 2018
Potency is a key optimization parameter for hemophilia A gene therapy product candidates. Optimization strategies include promoter engineering to increase transcription, codon optimization of mRNA to improve translation, and amino-acid substitution to ...
Harrison C. Brown, Philip M. Zakas, Stephan N. George, Ernest T. Parker, H. Trent Spencer, Christopher B. Doering   +5 more
doaj   +1 more source