Results 221 to 230 of about 7,775,245 (319)

The vector-regions of convex closed bodies

Mathematische Zeitschrift, 1934
openaire   +2 more sources

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

Advanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen, Weiyi Wang, Yang Wang, Yiqiang Wu, Xiaohong Liu, Wei Zhang, Juanjuan Ou   +6 more
wiley   +1 more source

Climate Change and Emerging Arboviral Threats in Saudi Arabia: Epidemiology, Vector Ecology, and One Health Preparedness. [PDF]

Infect Dis Rep
Hudu SA, Morad EA, Alhazimi GM, Jimoh AO.   +3 more
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

DRL-Based LEO Constellation Design for Regional Navigation Enhancement. [PDF]

Sensors (Basel)
Rui Z, Zeng F, Ouyang X, Chen L.
europepmc   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Molecular Atlas of Key Food Odorants Reveals Mixture‐Level Organization and Enables Generative Aroma Design

Advanced Science, EarlyView.
KFO‐Atlas reveals how real‐world aromas are organized as structured mixtures rather than individual molecules. Building on these principles, KFO‐Gen, a generative AI framework, designs perceptually valid aroma formulations and reconstructs meat‐like aromas exclusively from plant‐derived odorants, providing a foundation for mixture‐level studies and AI ...
Jingzhi Zhang, Huadong Xing, Antonella Di Pizio, Qinfei Ke, Xingran Kou, Dachuan Zhang   +5 more
wiley   +1 more source

From vaccine availability to effective deployment: Closing the arboviral vaccine access gap. [PDF]

Hum Vaccin Immunother
Tee KK, Mu D, Wang B, Xia X.
europepmc   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source