Results 61 to 70 of about 7,775,245 (319)
BMC Genomics, 2020 Background Rhodnius prolixus has become a model for revealing the molecular bases of insect sensory biology due to the publication of its genome and its well-characterized behavioural repertoire.
Jose Manuel Latorre-Estivalis +3 more
doaj +1 more source
Impact of ENSO 2016–17 on regional climate and malaria vector dynamics in Tanzania
Environmental Research Letters, 2019 Large scale modes of climate variability, including the El Niño Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD), have been shown to significantly impact mosquito-borne diseases in the Tropics, including malaria.
Katharina S. Kreppel +5 more
semanticscholar +1 more source
Targeted integration of a rAAV vector into the AAVS1 region
Virology, 2012 Adeno-associated virus (AAV) has been reported to integrate in a site-specific manner into chromosome 19 (a site designated AAVS1), a phenomenon that could be exploited for ex vivo targeted gene therapy. Recent studies employing LM-PCR to determine AAV integration loci; however, have, contrary to previous results with less reliable methods, concluded ...
Ward, Peter, Walsh, Christopher E.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Brain age vector: A measure of brain aging with enhanced neurodegenerative disorder specificity
Human Brain Mapping, 2022 Neuroimaging‐driven brain age estimation has become popular in measuring brain aging and identifying neurodegenerations. However, the single estimated brain age (gap) compromises regional variations of brain aging, losing spatial specificity across ...
Chen Ran +4 more
semanticscholar +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Tropical Medicine and Health, 2018 Background As Myanmar progresses towards lymphatic filariasis (LF) elimination, it is important to know how well the anti-filarial activities have performed.
Kyawt Mon Win +6 more
doaj +1 more source
EClinicalMedicine, 2021 Background Dengue is one of the most common vector-borne diseases globally, however, its burden is poorly quantified. Hence, we aimed to report the dengue burden in 195 countries and territories between 1990 and 2017, using data from the Global Burden of
Zhilin Zeng +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Regional biogeography of microbiota composition in the Chagas disease vector Rhodnius pallescens
Parasites & Vectors, 2019 Triatomine bugs are vectors of the protozoan parasite Trypanosoma cruzi, which causes Chagas disease. Rhodnius pallescens is a major vector of Chagas disease in Panama.
T. Kieran +7 more
semanticscholar +1 more source