Results 71 to 80 of about 8,311,474 (361)
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
IET Power Electronics, 2021 This paper presents a comparative analysis of the continuous space vector pulse width modulation and the discontinuous space vector pulse width modulation in terms of the switching losses and current ripple reduction for the unbalanced two‐phase four‐leg
Kaset Muangthong, Chakrapong Charumit
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Mirroring Vector Space Embedding for New Words
IEEE Access, 2021 Most embedding models used in natural language processing require retraining of the entire model to obtain the embedding value of a new word. In the current system, as retraining is repeated, the amount of data used for learning gradually increases.
Jihye Kim, Ok-Ran Jeong
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FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
On Linear Algebra Education [PDF]
İnönü Üniversitesi Eğitim Fakültesi Dergisi, 2009 Linear algebra is a basic course followed in mathematics, science, and engineering university departments.Generally, this course is taken in either the first or second year but there have been difficulties in teachingand learning.
Sinan AYDIN
doaj
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
On the decomposition of vector spaces
Linear Algebra and its Applications, 1986 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Diffeological vector spaces [PDF]
Pacific Journal of Mathematics, 2019 We study the relationship between many natural conditions that one can put on a diffeological vector space: being fine or projective, having enough smooth (or smooth linear) functionals to separate points, having a diffeology determined by the smooth linear functionals, having fine finite-dimensional subspaces, and having a Hausdorff underlying ...
J. Daniel Christensen, Enxin Wu
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Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Discrete Mathematics, 1980 Partitions of groups have been studied by several authors. J.W. Young proved in [6] that if an abelian group has a non-trivial partition, the group must be an elementary abelian p-group. Since such a group can be represented as the additive group of some V,,(p) -and U is a subgroup of V,(p) iff U is a subspace of V,(p) partitions of V,(q) is a ...
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