Results 81 to 90 of about 426,064 (264)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Informal Complete Metric Space and Fixed Point Theorems

open access: yesAxioms, 2019
The concept of informal vector space is introduced in this paper. In informal vector space, the additive inverse element does not necessarily exist. The reason is that an element in informal vector space which subtracts itself cannot be a zero element ...
Hsien-Chung Wu
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Neutrosophic Vector Spaces [PDF]

open access: yesNeutrosophic Sets and Systems, 2014
The objective of this paper is to study neutrosophic vector spaces. Some basic definitions and properties of the classical vector spaces are generalized. It is shown that every neutrosophic vector space over a neutrosophic field (resp.
A.A.A. Agboola, S.A. Akinleye
doaj  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

O fragmentado e tortuoso processo de construção dos conceitos de vetor e escalar

open access: yesRevista Brasileira de Ensino de Física
O presente trabalho é uma tentativa de chamar a atenção para a forma inadequada da construção dos conceitos de vetor e escalar apresentados na maioria dos livros de física no nível universitário.
Osman Rosso Nelson   +1 more
doaj   +1 more source

Two-Vector Spaces and Groupoids [PDF]

open access: yesApplied Categorical Structures, 2010
The paper is a specification of the groupoidification program of Baez and Dolan. The author uses the Kapranov-Voevodsky definition of a two vectorspace: 2-vectors are \(k\)-tuples of vector spaces, direct sum is addition and tensor product is multiplication.
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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