Results 51 to 60 of about 49,109 (230)

Monitoreo de enfermedades tropicales mediante Sistema de Información Geográfica en la ciudad de Guayaquil

Serie Científica de la Universidad de las Ciencias Informáticas, 2023
Las enfermedades vectoriales en Ecuador son influenciadas por la presencia de diferentes especies de vectores, causantes de Dengue, Zika, Chicungunya, Mayaro, y de parasitosis, transmitidas por otras variantes de mosquitos como Anopheles spp que causa ...
Mirella Carmina Ortiz-Zambrano, Tania J. Peralta Guaraca, Alfonso A. Guijarro-Rodríguez, Gladys C. Jácome-Morales, Juan Andrés Quinde Bayas   +4 more
doaj  

Improving approximation of domain-focused, corpus-based, lexical semantic relatedness [PDF]

, 2017
Semantic relatedness is a measure that quantifies the strength of a semantic link between two concepts. Often, it can be efficiently approximated with methods that operate on words, which represent these concepts.
Rybinski, Maciej
core   +1 more source

Empleo de Adeno Vectores Asociados para el Tratamiento de la Enfermedad de Tay Sachs

Ciencia Latina Revista Científica Multidisciplinar, 2023
Tay Sachs es una enfermedad autosómica recesiva que pertenece al grupo de las GM2 gangliosidosis y afecta gravemente al SNC. Las terapias génicas que emplean Adeno Vectores virales asociados recombinantes han arrojado resultados promisorios en cuanto al restablecimiento de la actividad de la enzima deficiente en esta enfermedad y de esta manera mejorar
Sandy Lorena Plata Mora, Mary Luz Yaya Lancheros   +1 more
openaire   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Mutant alleles associated to chloroquine and sulfadoxine-pyrimethanime resistance in Plasmodium falciparum of the Ecuador-Peru and Ecuador-Colombia borders

Revista Peruana de Medicina Experimental y Salud Pública, 2014
The frequency of mutations in pfCRT and DHFR/DHPS genes of Plasmodium falciparum associated with resistance to chloroquine and sulfadoxine-pyrimethamine was evaluated in 83 strains from the districts of Esmeralda and Machala, located on the borders of ...
Nancy Arróspide, Gisely Hijar-Guerra, Doménica de Mora, César Eduardo Diaz-Cortéz, Raúl Veloz-Perez, Sonia Gutierrez, César Cabezas _Sánchez   +6 more
doaj   +1 more source

Investigación del virus de importancia médica y veterinaria transmitidos por culicoides [PDF]

, 2017
The first paper comprises the study of the Bluetongue virus (BTV) and Epizootic Hemorrhagic Virus (EHDV), two orbiviruses transmitted by Culicoides biting midges, and causative agents of disease in wild and domestic ruminants.
Mosquera Bolaños, Juan Daniel
core  

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Primer reporte de Aedes (Stegomyia) albopictus (Skuse) en la Orinoquia colombiana

Biomédica: revista del Instituto Nacional de Salud, 2019
Introducción. Aedes albopictus es vector de arbovirus, como Flavivirus, Alphavirus, Bunyavirus, Phlebovirus, Orbivirus y Picornavirus. Muchos son agentes etiológicos de enfermedades en humanos. Actualmente, A.
Malenna Camacho-Gómez, Liliana Patricia Zuleta   +1 more
doaj   +1 more source

Control of Chagas disease vectors Control de vectores de la enfermedad de Chagas

Salud Pública de México, 2003
Most Latin American countries are making dramatic progress in controlling Chagas disease, through a series of national and international initiatives focusing on elimination of domestic populations of Triatominae, improved screening of blood donors, and clinical support and treatment of persons infected with Trypanosoma cruzi.
JM Ramsey, CJ Schofield
openaire   +1 more source

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas   +5 more
wiley   +1 more source