Results 71 to 80 of about 4,245,387 (333)

A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation

open access: yesNature Communications, 2020
IKK2 is the main mediator of the NF-kappaB pathway. Here, the authors demonstrate that LMP1 sustains the survival of Epstein-Barr virus-transformed human B cells and post-transplant lymphoma through IKK2 that induces JNK signaling through TPL2.
Stefanie Voigt   +6 more
doaj   +1 more source

Metagenomic sequencing characterizes a wide diversity of viruses in field mosquito samples in Nigeria

open access: yesScientific Reports, 2022
Mosquito vectors are a tremendous public health threat. One in six diseases worldwide is vector-borne transmitted mainly by mosquitoes. In the last couple of years, there have been active Yellow fever virus (YFV) outbreaks in many settings in Nigeria ...
Judith U. Oguzie   +29 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Nutritional sex-specificity on bacterial metabolites during mosquito (Aedes aegypti) development leads to adult sex-ratio distortion

open access: yesCommunications Biology
Mosquitoes rely on their microbiota for B vitamin synthesis. We previously found that Aedes aegypti third-instar larvae cleared of their microbiota were impaired in their development, notably due to a lack of folic acid (vitamin B9).
Ottavia Romoli   +6 more
doaj   +1 more source

On the interpretation of weight vectors of linear models in multivariate neuroimaging

open access: yesNeuroImage, 2014
The increase in spatiotemporal resolution of neuroimaging devices is accompanied by a trend towards more powerful multivariate analysis methods. Often it is desired to interpret the outcome of these methods with respect to the cognitive processes under ...
S. Haufe   +6 more
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The flag f-vectors of Gorenstein* order complexes of dimension 3 [PDF]

open access: yes, 2011
We characterize the cd-indices of Gorenstein* posets of rank 5, equivalently the flag f-vectors of Gorenstein* order complexes of dimension 3. As a corollary, we characterize the f-vectors of Gorenstein* order complexes in dimensions 3 and 4.
Murai, Satoshi, Nevo, Eran
core  

Rates of DNA Sequence Profiles for Practical Values of Read Lengths

open access: yes, 2016
A recent study by one of the authors has demonstrated the importance of profile vectors in DNA-based data storage. We provide exact values and lower bounds on the number of profile vectors for finite values of alphabet size $q$, read length $\ell$, and ...
Chang, Zuling   +3 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Particle Swarm Optimization Framework for Low Power Testing of VLSI Circuits

open access: yes, 2011
Power dissipation in sequential circuits is due to increased toggling count of Circuit under Test, which depends upon test vectors applied. If successive test vectors sequences have more toggling nature then it is sure that toggling rate of flip flops is
Khosla, Arun   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy