Results 41 to 50 of about 110,493 (310)

The archaeological sublime: history and architecture in Piranesi's drawings [PDF]

open access: yes, 2006
Thesis (Master)--İzmir Institute of Technology, Architecture, İzmir, 2006Includes bibliographical references (leaves:144-176)Text in English; Abstract: Turkish and Englishxxi, 176 leavesIn the architectural, historical, and archaeological context of the ...
Ek, Fatma İpek
core   +1 more source

Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice

open access: yesMolecular Therapy: Nucleic Acids, 2018
Viral vectors are rapidly being developed for a range of applications in research and gene therapy. Prototype foamy virus (PFV) vectors have been described for gene therapy, although their use has mainly been restricted to ex vivo stem cell modification.
John R. Counsell   +18 more
doaj   +1 more source

Parkinson’s Disease Detection by Processing Different ANN Architecture Using Vocal Dataset

open access: yesEurasian Journal of Science and Engineering, 2023
Parkinson’s Disease (PD) is a long-standing neurodegenerative condition of the central nervous system that mainly affects the motor system and origins full or partial damage in behavior, speech, motor reflexes, mental processing, and other energetic ...
Yusra Mohammed M. Salih   +1 more
doaj   +1 more source

In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector

open access: yesCell Reports, 2015
Adeno-associated virus (AAV) vectors have emerged as a gene-delivery platform with demonstrated safety and efficacy in a handful of clinical trials for monogenic disorders.
Eric Zinn   +11 more
doaj   +1 more source

Neural network architectures for vector prediction [PDF]

open access: yesProceedings of the IEEE, 1996
A vector predictor is an integral part of a predictive vector quantization coding scheme. The conventional techniques for designing a nonlinear predictor are extremely complex and suboptimal due to the absence of a suitable model for the source data. We investigated several neural network architectures that can be used to implement a nonlinear vector ...
Rizvi, S. A.   +2 more
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Multifunctional SEVA shuttle vectors for actinomycetes and Gram‐negative bacteria

open access: yesMicrobiologyOpen, 2020
Actinomycetales, such as the genus Streptomyces, are well‐known cell factories employed to produce a wide variety of secondary metabolites for industrial use.
Coral García‐Gutiérrez   +6 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

MADServer: An Architecture for Opportunistic Mobile Advanced Delivery [PDF]

open access: yes, 2012
Rapid increases in cellular data traffic demand creative alternative delivery vectors for data. Despite the conceptual attractiveness of mobile data offloading, no concrete web server architectures integrate intelligent offloading in a production-ready ...
Anders Lindgren   +11 more
core   +1 more source

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