Results 271 to 280 of about 717,961 (381)

Immune checkpoint inhibitor resistance in non-small cell lung cancer: limits of vascular endothelial growth factor inhibition and new directions. [PDF]

J Thorac Dis
Kaneda H.
europepmc   +1 more source

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1.

Blood, 1996
B. Barleon, S. Sozzani, Dan Zhou, H. Weich, A. Mantovani, D. Marmé   +5 more
semanticscholar   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

The Current Role of Antiangiogenics in Colorectal Cancer. [PDF]

Int J Mol Sci
Basile D, Di Nardo P, Daffinà MG, Cortese C, Giuliani J, Aprile G.   +5 more
europepmc   +1 more source

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain.

Journal of Clinical Investigation, 2000
Zhenggang Zhang, Li Zhang, Q. Jiang, RuiLan Zhang, Kenneth R. Davies, Cecylia Powers, N. Bruggen, M. Chopp   +7 more
semanticscholar   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Treatment results switching from aflibercept to bevacizumab in wet age-related macular degeneration. [PDF]

Int J Ophthalmol
Kananen F.
europepmc   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

VEGF-A and Tenascin-C produced by S100A4[superscript +] stromal cells are important for metastatic colonization

, 2011
Raghu Kalluri, Joyce T. O’Connell, Hikaru Sugimoto, Vesselina G. Cooke, Brian A. MacDonald, Ankit I. Mehta, Valerie S. LeBleu, Rajan Dewar, Rafael Malagoli Rocha, Helena Brentani, Murray B. Resnick, Eric G. Neilson, Michael Zeisberg   +12 more
openalex   +1 more source

Impact of alendronate and VEGF-antisense combined treatment on highly VEGF-expressing A431 cells

, 2009
Medge Mongerard-Coulanges, Evelyne Migianu‐Griffoni, Marc Lecouvey, Béatrice Jollès   +3 more
openalex   +2 more sources