Results 91 to 100 of about 2,468,898 (371)

Role of the Angiogenic Factors in Cholangiocarcinoma

open access: yesApplied Sciences, 2019
Angiogenesis plays a fundamental role in tumor growth and progression. It is regulated by several growth factors, including vascular endothelial growth factor protein family (VEGF) and its receptors, which are probably the most important factors ...
Romina Mancinelli   +5 more
doaj   +1 more source

Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients.

open access: yesAJP - Renal Physiology, 2008
Interstitial cystitis (IC) is a chronic and painful bladder syndrome of unknown cause with no reliable biological marker or effective therapy. Vascular endothelial growth factor (VEGF), which plays a key role in bladder inflammation, is closely ...
Ricardo Saban   +10 more
semanticscholar   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

open access: yesAdvanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu   +12 more
wiley   +1 more source

Inhibition of VEGF-Dependent Multistage Carcinogenesis by Soluble EphA Receptors

open access: yesNeoplasia: An International Journal for Oncology Research, 2003
Elevated expression of Eph receptors has long been correlated with the growth of solid tumors. However, the functional role of this family of receptor tyrosine kinases in carcinogenesis and tumor angiogenesis has not been well characterized.
Nikki Cheng   +9 more
doaj   +1 more source

Stochastic models of the binding kinetics of VEGF-A to VEGFR1 and VEGFR2 in endothelial cells [PDF]

open access: yesarXiv, 2016
Vascular endothelial growth factor receptors (VEGFRs) are receptor tyrosine kinases (RTKs) that regulate proliferation, migration, angiogenesis and vascular permeability of endothelial cells. VEGFR1 and VEGFR2 bind vascular endothelial growth factors (VEGFs), inducing receptor dimerisation and activation, characterised by phosphorylation of tyrosine ...
arxiv  

A Thermodynamic Model for Receptor Clustering [PDF]

open access: yes, 1999
Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavior between near-neighbor receptor molecules; the properties of this cooperative process clearly affects the signal transduction.
arxiv   +1 more source

Electrical stimulation directly induces pre-angiogenic responses in vascular endothelial cells by signaling through VEGF receptors

open access: yesJournal of Cell Science, 2003
Controlling angiogenesis is crucial. Growth factors and cytokines are key regulators but a full understanding remains elusive. Endogenous electrical potential differences exist within and around the vasculature, both in relation to blood flow and in ...
Min Zhao   +4 more
semanticscholar   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

open access: yesAdvanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan   +4 more
wiley   +1 more source

Expression of VEGF receptors VEFGR-1 and VEGFR-2, angiopoietin receptors Tie-1 and Tie-2 in chorionic villi tree during early pregnancy.

open access: yesFolia Histochemica et Cytobiologica, 2010
The aim of this study was to determine the expression of VEGF and its receptors in placentas from normal pregnancies between 22 days p.c. and 48 days p.c. of very early pregnancy.
Ramazan Demir
doaj   +1 more source

mRNA Expression of VEGF and Its Receptors in Fallopian Tubes of Women with Ectopic Pregnancies [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2015
Background Establishment of viable pregnancy requires embryo implantation and placentation. Ectopic pregnancy (EP) is a pregnancy complication which occurs when an embryo implants outside of the uterine cavity, most often in a fallopian tube.
Nafise Zarezade   +5 more
doaj   +1 more source

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